Evidence map›Paper›PMID 41244277›Full record

ArticleASM case reports2025

Cefepime failure for the treatment of cefepime-susceptible, KPC-producing

Jordynne Morelan, Rong Hou, Robin Chamberland, Christian M Gill

Abstract readCase Reports
In one paragraph

Article in ASM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jordynne MorelanDepartment of Pharmacy, SSM Health Saint Louis University Hospital, St. Louis, Missouri, USA.
Rong HouDepartment of Internal Medicine, Saint Louis University , St. Louis, Missouri, USA.
Robin ChamberlandDepartment of Pathology, Saint Louis University, St. Louis, Missouri, USA.
Christian M GillDepartment of Pharmacy, SSM Health Saint Louis University Hospital, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-3606-0761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The growing incidence of carbapenem-resistant Enterobacterales (CRE) poses a challenge to clinical practice. Despite some Case Summary: Here, we present a case of clinical failure after cefepime treatment for a KPC-producing Conclusion: This case adds to the growing literature supporting the use of carbapenemase testing for Enterobacterales isolates that demonstrate resistance to one or more carbapenems to guide therapy. Until confirmatory clinical data are available, clinicians and laboratorians must consider selective reporting or other strategies in the setting of contradictory phenotypic susceptibility data and genotypic resistance markers.

Indexed as

KPCmolecular diagnosticsurinary tract infections

Identifiers

PMID41244277
PMCPMC12584169

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.