Evidence map›Paper›PMID 41244413›Full record

ArticleACS omega2025

Development of a Novel HIF-2α PET Tracer for Noninvasive Tumor Hypoxia Imaging.

Yanli Wang, Yongle Wang, Ping Bai, Jian Cui, Yanting Zhou, Hongyan Li, Lili Wu, Haiyan Wang, Shiming Bai, Ru Ya and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yanli WangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0001-5807-3497
Yongle WangSchool of Pharmacy, Minzu University of China, Beijing 100081, China.
Ping BaiDepartment of Respiratory and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Jian CuiSchool of Pharmacy, Minzu University of China, Beijing 100081, China.
Yanting ZhouDepartment of Respiratory and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Hongyan LiDepartment of Respiratory and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Lili WuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Haiyan WangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0002-9231-3869
Shiming BaiInner Mongolia Academy of Science and Technology, 70 Zhaowuda Road, Hohhot 010010, China.
Ru YaInner Mongolia Academy of Science and Technology, 70 Zhaowuda Road, Hohhot 010010, China.
Xiaoye BaiCollege of Modern Agriculture and Bioengineering, Yangtze Normal University, Chongqing 408102, China.
Zhanru LiuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Tonghua LiuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia is a major driver of tumor progression and therapeutic resistance, with hypoxia-inducible factor 2α (HIF-2α) playing a critical regulatory role. To address the current lack of noninvasive imaging tools for HIF-2α, we developed [

Identifiers

PMID41244413
PMCPMC12613116

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.