Evidence map›Paper›PMID 41244801›Full record

ArticleFrontiers in medicine2025

Molecular identification and phenotypic study of a novel

Shichun Shen, Jungao Huang, Haimei Qi, Zezhang Liu, Wenqian Zhang, Xianping Yuan, Zhuling Zhang, Haijun Chen, Xinxing Xie, Lin Xiao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shichun Shen *Department of Medical Genetics, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Jungao Huang *Department of Medical Genetics, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Haimei QiDepartment of Clinical Laboratory, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Zezhang LiuBGI Genomics, Shenzhen, China.
Wenqian ZhangBGI Genomics, Shenzhen, China.
Xianping YuanObstetrical Department, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Zhuling ZhangObstetrical Department, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Haijun ChenDepartment of Medical Genetics, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Xinxing XieDepartment of Medical Genetics, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Lin XiaoDepartment of Medical Genetics, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Junkun ChenDepartment of Medical Genetics, Ganzhou Maternal and Child Health Hospital, Ganzhou, China.
Liyun SongDepartment of Clinical Laboratory, Ganzhou People's Hospital, Ganzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: β-thalassemia is a prevalent genetic disorder in the Gannan region, Southern China. Mutations in the 5' untranslated region of the β-globin gene are associated with diverse clinical phenotypes, posing challenges for effective prevention strategies in this region. Methods: In this study, carriers of the Results: Among the 192,720 individuals tested, 75 carriers of the Conclusion: The carrier frequency of

Indexed as

5′ untranslated regionhematological parametersminimum free energynovel mutationβ-globin gene

Identifiers

PMID41244801
PMCPMC12611677

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.