Evidence map›Paper›PMID 41245412›Full record

SynthesisFrontiers in nutrition2025

The gut microbiota of Indigenous populations in the context of dietary westernization: a systematic review and meta-analysis.

Camille Daunizeau, Maximilien Franck, Amélie Boutin, Marianne Ruel, Natalia Poliakova, Pierre Ayotte, Richard Bélanger

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Camille DaunizeauPopulation Health and Optimal Health Practices Research Unit, CHU de Québec Research Centre, Quebec city, QC, Canada.
Maximilien FranckResearch Center on Aging, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Amélie BoutinPopulation Health and Optimal Health Practices Research Unit, CHU de Québec Research Centre, Quebec city, QC, Canada.
Marianne RuelLibrary, Université Laval, Quebec city, QC, Canada.
Natalia PoliakovaPopulation Health and Optimal Health Practices Research Unit, CHU de Québec Research Centre, Quebec city, QC, Canada.
Pierre AyottePopulation Health and Optimal Health Practices Research Unit, CHU de Québec Research Centre, Quebec city, QC, Canada.
Richard BélangerPopulation Health and Optimal Health Practices Research Unit, CHU de Québec Research Centre, Quebec city, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Indigenous populations worldwide are undergoing dietary transitions from traditional patterns toward westernized diets, influencing gut microbiota diversity and composition, with potential implications for health. Objective: This systematic review and meta-analysis aimed to compare gut microbiota diversity and composition among Indigenous populations following traditional versus westernized dietary patterns. Methods: A comprehensive literature search was conducted in March 2024 and updated on February 25, 2025 across databases, including All Ovid MEDLINE®, Embase, Web of Science, CAB Abstracts, and Food Science and Technology Abstracts, along with searches of gray literature sources. Eligibility criteria included observational studies comparing gut microbiota diversity and composition between traditional and westernized diets among healthy Indigenous adults (≥16 years) without chronic diseases. Two reviewers independently performed study selection, data extraction, and risk of bias assessment using the ROBINS-E tool. Data were synthesized using random effects models, specifically applying the restricted maximum likelihood estimator to calculate between-study variance (τ Results: Of 19,836 articles identified, nine studies ( Conclusion: The observed heterogeneity likely reflects methodological differences, ecological variability, and the diversity of traditional diets and varying patterns of dietary transition. Longitudinal research is needed to better understand how dietary transitions affect gut microbiota over time in Indigenous populations. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024597804.

Indexed as

gut microbiotaIndigenous populationsmeta-analysisobservational studiessystematic reviewtraditional dietwesternized diet

Identifiers

PMID41245412
PMCPMC12612841

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.