Evidence map›Paper›PMID 41245451›Full record

ArticleFrontiers in plant science2025

Integrated metabolomic and transcriptomic analyses elucidate anthocyanin-mediated flesh coloration mechanisms in red-fleshed pear.

Mengning Du, Yanan Wang, Xiangzhan Zhang, Suke Wang, Yanli Su, Long Wang, Huabai Xue

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Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengning Du *National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, China.
Yanan Wang *National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, China.
Xiangzhan ZhangNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, China.
Suke WangNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, China.
Yanli SuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, China.
Long WangNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, China.
Huabai XueNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The red-fleshed pears embody a unique and invaluable genetic resource. However, the specific types of metabolites in red-fleshed pears and its molecular mechanisms remain largely unknown. To understand these, targeted carotenoid and anthocyanin metabolomics as well as transcriptomics analyses were carried out in this study, using red-fleshed material 'M2' and white-fleshed material 'XM'. The results showed that the concentrations and proportions of anthocyanins are the predominant determinants of the flesh coloration in red and white cultivars, rather than carotenoids. Notably, cyanidin-3-O-galactoside is the main anthocyanins enriched in red-fleshed pear 'M2'. Moreover, a total of 6168 common differentially expressed genes (DEGs) between red and white flesh tissues were identified, KEGG and GO enrichment analyses showed that 42 DEGs were significantly enriched in the flavonoid and anthocyanin biosynthesis pathways. Correlation analysis of the transcriptome and metabolome revealed associations between core metabolites and genes, leading to the identification of several key transcription factors potentially involved in anthocyanin biosynthesis, such as

Indexed as

anthocyaninpearpigmentationred-fleshedtranscriptome and metabolome

Identifiers

PMID41245451
PMCPMC12615504

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.