Evidence map›Paper›PMID 41245513›Full record

ReviewInternational journal of pharmaceutics: X2025

Multifunctional nanosponges in cancer therapy: Integrating targeted drug delivery and theranostic potential.

Sandesh Ramchandra Jadhav, Ashutosh Gupta, Viola Colaco, Moumita Saha, Amatha Sreedevi, Deepanjan Datta, Sudheer Moorkoth, Virendra S Ligade, Namdev Dhas

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of pharmaceutics: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Toxicity of nanostructures in drug delivery applications.Pharmaceutical science advances · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sandesh Ramchandra JadhavDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Ashutosh GuptaDepartment of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Viola ColacoDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Moumita SahaDepartment of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Amatha SreedeviDepartment of Pharmaceutical Regulatory Affairs, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Deepanjan DattaDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Sudheer MoorkothDepartment of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Virendra S LigadeDepartment of Pharmaceutical Regulatory Affairs, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Namdev DhasDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains a leading cause of mortality, with conventional therapies often limited by systemic toxicity, poor drug bioavailability, and the emergence of drug resistance. Multifunctional nanosponges represent an innovative nanotherapeutic platform for cancer management, integrating targeted drug delivery and theranostic functionalities to overcome limitations of conventional therapies. These nanosponges exhibit high encapsulation efficiency for hydrophilic and hydrophobic therapeutics and biologics. Surface functionalization with ligands enables selective tumor targeting

Indexed as

Cancer therapyNanospongesPharmacokineticsPhotodynamic therapyPhotothermal therapyTargeted drug delivery

Identifiers

PMID41245513
PMCPMC12615323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.