Evidence map›Paper›PMID 41246010›Full record

ArticleFrontiers in cardiovascular medicine2025

Beat-to-beat coronary wave intensity analysis: implications of backward waves originating from microvascular.

Xinzhou Xie, Peng Han, Tiantong Yu, Zixi Huang, Heqiang Lin, Songyun Xie, Bohui Zhang, Shuai Zhao, Che Wang, Chengxiang Li and 2 more

Abstract read
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In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xinzhou Xie *Department of Information Engineering, School of Electronics and Information, Northwestern Polytechnical University, Xi'an, Shaanxi, China.
Peng Han *Department of Cardiology, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, China.
Tiantong Yu *Department of Cardiology, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, China.
Zixi HuangDepartment of Information Engineering, School of Electronics and Information, Northwestern Polytechnical University, Xi'an, Shaanxi, China.
Heqiang LinDepartment of Information Engineering, School of Electronics and Information, Northwestern Polytechnical University, Xi'an, Shaanxi, China.
Songyun XieDepartment of Information Engineering, School of Electronics and Information, Northwestern Polytechnical University, Xi'an, Shaanxi, China.
Bohui ZhangDepartment of Cardiology, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, China.
Shuai ZhaoDepartment of Cardiology, Air Force Hospital of Western Theater Command, Chengdu, Sichuan, China.
Che WangSchool of Public Health, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Chengxiang LiDepartment of Cardiology, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, China.
Yan ChenDepartment of Cardiology, No. 971 Hospital of the PLA Navy, Qingdao, Shandong, China.
Kun LianDepartment of Cardiology, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: While coronary wave intensity analysis (cWIA) offers a promising way to assess myocardial and microvascular function by decomposing microvascular-originated backward waves, its clinical utility is currently limited by complex data acquisition and unclear influence of varying hemodynamic factors (adenosine, stenosis and vessel type). Methods: This study introduces an angiography-based cWIA method and clarifies how those hemodynamic factors impact cWIA parameters. This retrospective study included 124 patients with 125 target vessels, for which beat-to-beat cWIA was successfully performed at rest and during adenosine-induced hyperemia. Results: Our analysis revealed a strong and significant correlation between cumulative backward compression wave intensity ( Discussion: The clinical feasibility of a convenient cWIA method was validated, and the impact of various hemodynamic factors on quantitative parameters of cWIA were analyzed, providing strong support for the clinical application of cWIA.

Indexed as

adenosine-induced changescoronary physiologycoronary wave intensity analysishemodynamicmyocardial-coronary interaction

Identifiers

PMID41246010
PMCPMC12611823

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.