ArticleJournal of diabetes research2025
Effect of Glucagon-Like Peptide-1 Receptor Agonists on Renal and Cardiovascular Risk Factors in Patients With Type 2 Diabetes Mellitus: A Retrospective Study.
Article in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Aims: This research explores the impact of glucagon-like peptide-1 receptor agonist (GLP-1RA) on key risk factors associated with kidney and cardiovascular diseases in Indigenous (Aboriginal and/or Torres Strait Islander) and non-Indigenous adults living with Type 2 diabetes, receiving care at a regional health facility in North Queensland, Australia. Methods: This retrospective study included patients who attended the diabetes clinic at a regional hospital between January 2016 and January 2020. Data was extracted from electronic medical records. Basic demographic characteristics along with blood pressure, body weight, BMI, urine albumin creatinine ratio (UACR), serum creatinine, estimated glomerular filtration rate (eGFR), HbA1c, total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride levels were retrieved from initial presentation, 6 months, and 12 months post. Data was analyzed using IBM SPSS 28 with appropriate statistical tests applied. Results: The study involved a total of 164 patients. GLP-1RA use resulted in a significant reduction of HbA1c between 0 and 6 months (8.7%-7.9%, Conclusions: This study affirms the effectiveness of GLP-1RAs as a glycemic control agent with an additional benefit of weight reduction across a 12-month period in adult T2DM patients. No effect on other cardiovascular parameters apart from weight or renal risk factors was observed. Further investigation into the influence of GLP-1RAs on these would be beneficial.
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