ArticleThe Pan African medical journal2025
Tuberculosis in transit: risk factors in Tanzania's high-mobility border regions.
Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Prevalence and determinants of tuberculosis and COVID-19 among patients with presumptive tuberculosis in a Nigerian tertiary hospital.BMC infectious diseases · 2026Article
- Analysis of rpoB mutations associated with rifampicin resistance in Mycobacterium tuberculosis isolates in Malawi.BMC infectious diseases · 2026Article
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Abstract
Introduction: tuberculosis remains a leading infectious killer in low- and middle-income countries. Tanzania's cross-border, high-mobility regions present persistent control challenges. Methods: we recruited 400 adults (200 bacteriologically confirmed pulmonary tuberculosis cases and 200 presumptive non-tuberculosis controls) from six regions between November 2019 and December 2021. Data from structured questionnaires and medical records were analyzed with χ Results: most participants were predominantly male (55.6%) and aged 21-50 years (77.8%). HIV co-infection was the strongest predictor of tuberculosis (AOR=1.52; 95% CI; 1.15-2.21; p=0.003). Household crowding (≥4 residents) (AOR=1.44; 95% CI; 1.03-2.03; p=0.032), poor ventilation (AOR=1.40; 95% CI; 1.01-1.95; p=0.043), and biomass-fuel use (AOR=1.37; 95% CI; 1.00-1.88; p=0.049) independently increased risks for pulmonary tuberculosis. Behavioral factors, smoking (AOR=1.68; 95% CI; 1.12-2.50; p=0.012) and alcohol consumption (AOR=1.57; 95% CI; 1.07-2.31; p=0.021) showed similar associations. Regional tuberculosis prevalence was higher in mobile populations (χ Conclusion: pulmonary tuberculosis in Tanzania's high-mobility regions is driven by HIV co-infection, overcrowded and poorly ventilated dwellings, biomass-fuel smoke, and high-risk behaviors, compounded by diagnostic delays. Strengthening integrated TB-HIV services, enhancing community awareness, and implementing geographically targeted screening are pivotal to accelerating progress toward national End-TB targets.
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