ReviewCureus2025
Recent Advances in Pediatric Infectious Diseases: A Review of Diagnostic and Therapeutic Strategies.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pediatric infectious diseases remain the leading cause of significant morbidity and mortality globally, especially among children under the age of five. Despite advances in vaccination and antimicrobial therapy, difficulties such as delayed diagnosis, increasing antimicrobial resistance, and socioeconomic inequalities constrain effective management. This review summarizes recent progress in molecular diagnostics, such as polymerase chain reaction, multiplex assays, and next-generation sequencing, and the contribution of biomarkers and host gene expression profiling to the discrimination between bacterial and viral infections to inform antibiotic stewardship. New therapeutic principles, such as immunomodulatory drugs and personalized medicine strategies, such as pharmacogenomics and therapeutic drug monitoring, are promising to enhance outcomes. Progress in pediatric vaccine antigens and schedules has further minimized the disease burden across the world. Moreover, digital health technologies and telemedicine are revolutionizing access and management of pediatric infections. However, access continues to be restricted by limited pediatric-specific clinical trials, costs, and issues of infrastructure. This integrated synthesis bridges a major knowledge gap by combining diagnostic and therapeutic innovations specific to children, providing insights to maximize clinical practice and guide future studies to promote child health globally.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.