Evidence map›Paper›PMID 41247452›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Terpene-augmented novasomal carriers for trans-tympanic drug delivery: a comprehensive optimization and in vivo evaluation.

Sadek Ahmed, Ali Fayez, Heba Attia, Doaa Ahmed El-Setouhy

Abstract read
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Innovative hyaluronic acid-decorated quatsomes for enhanced renal targeting: design, optimization andJournal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sadek AhmedDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini, Cairo, Egypt, P.O. Box 11562. sadek.sadek@pharma.cu.edu.eg.ORCID http://orcid.org/0000-0002-0190-9502
Ali FayezMinistry of Health, Jeddah, Kingdom of Saudi Arabia, Jeddah, Saudi Arabia.
Heba AttiaDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Doaa Ahmed El-SetouhyDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini, Cairo, Egypt, P.O. Box 11562.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Otitis media (OM) is a frequent infectious condition that affects the middle ear especially in children. The purpose of this project was to create fenchone-augmented novasomes to enhance the trans-tympanic penetration of levofloxacin (LFX) and improve its antibacterial efficacy. Novasomes were formulated using the ethanol injection technique and optimized using a 2

Indexed as

Anti-Bacterial AgentsDrug CarriersLevofloxacinTerpenesAnimalsDrug Delivery SystemsDrug LiberationLiposomesMaleMicrobial Sensitivity TestsOtitis MediaParticle SizePseudomonas aeruginosaRabbitsStaphylococcus aureusAnti-Bacterial AgentsDrug CarriersLevofloxacinLiposomesTerpenesBiofilm inhibitionIn vivo permeationLevofloxacinNovasomesRheology

Identifiers

PMID41247452
PMCPMC13046594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.