ArticleJournal of prevention (2022)2026
Effectiveness of a School-Based Drug Prevention Program: Tú Decides 2.0.
Article in Journal of prevention (2022), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05950074 (Update and Digitalization of a Universal School-based Prevention Intervention for Drug Initiation and Use), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Update and Digitalization of a Universal School-based Prevention Intervention for Drug Initiation and Use: the "It´s Up To You" Program
Who cites it
1 citing paper in PubMed.
- The Short-Term Change in Knowledge of Cannabis-Related Risks After a Brief Curriculum-Integrated School Intervention Among Adolescents: A Quasi-Experimental Pre-Post Study.Healthcare (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Adolescent substance use remains a significant public health concern in Spain. This study evaluates the effectiveness of "Tú Decides 2.0," an updated school-based drug prevention program, in reducing substance use among Spanish adolescents. A nine-month, two-arm, quasi-experimental controlled trial was conducted involving 2251 adolescents (aged 12-17) from 13 secondary schools in three Spanish regions. The intervention group (n = 1209) received the "Tú Decides 2.0" program, while the control group (n = 1042) underwent only assessment sessions. Primary outcomes were past 30-day use of alcohol, tobacco, e-cigarettes, and cannabis at three-month follow-up. Overall, prevalence of use was lower than the national mean data. GEE analyses following an ITT approach showed significant effects of the program in reducing the prevalence of self-reported e-cigarette use in the intervention group compared to the control group in 2nd (OR = 0.54; CI = 0.32; 0.90) and 4th (OR = 0.33; CI = 0.27; 1.14) CSE years. Significant effects were also found in reducing the prevalence of alcohol (OR = 0.57; CI = 0.32; 1.00) and tobacco (OR = 0.57; CI = 0.37; 0.88) use at three-months follow-up among students in 2nd CSE year. No significant effects were observed for cannabis nor for the 1st and 3rd CSE years. Models conducted using Multiple Imputation yielded similar results. The "Tú Decides 2.0" program demonstrated effectiveness in reducing both the incidence and prevalence of e-cigarette, alcohol and tobacco use among Spanish adolescents. These findings support the implementation of updated, digitalized school-based interventions for substance use prevention.Trial Registration ClinicalTrials.gov Registry (#NCT05950074).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.