Evidence mapPaperPMID 41247604Full record

ReviewMedical oncology (Northwood, London, England)2025

Wearable nanopatch platforms for real-time miRNA sensing and editing: a vision for next-generation cancer management.

K P Ameya, Kehinde Ross, Durairaj Sekar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

K P AmeyaRNA Biology Lab, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai, 600077, India.
Kehinde RossSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
Durairaj SekarRNA Biology Lab, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai, 600077, India. duraimku@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer therapy is undergoing an evolution where on-the-spot, adaptable, and fully personalized treatment will soon be in vogue. Central to this progress are microRNAs (miRNAs), which serve as key regulators in cancer biology. Their altered expression profiles not only provide valuable biomarkers enabling early cancer detection but also offer dynamic molecular targets for therapeutic intervention. miRNAs are key regulators frequently used as cancer biomarkers, enabling early detection and timely intervention. Recent advances in wearable biosensing technologies have ushered in innovative platforms such as smart bandages, flexible electronic tattoos, and microneedle arrays that can monitor molecular biomarkers, including miRNAs, directly from interstitial fluid in a minimally invasive way. Emerging therapeutic applications now include wearable miRNA-editing patches that hold promise to correct dysregulated miRNAs at the disease site. This approach moves beyond static, standard treatments toward dynamic and adaptive cancer therapies tailored in real time. This review discusses the scientific basis of miRNA roles in cancer, recent technological breakthroughs in wearable biosensing and gene editing, and key translational challenges-such as biocompatibility, targeted delivery, and regulatory approvals-that must be addressed to realize the potential of truly personalized next-generation cancer therapy platforms.

Indexed as

Biosensing TechniquesGene EditingMicroRNAsNeoplasmsWearable Electronic DevicesBiomarkers, TumorHumansBiomarkers, TumorMicroRNAsBiosensorCancerDiagnosismiRNAmiRNA editingTherapeutics

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.