ReviewAnnals of medicine2025
Anticancer potential of dietary fiber for colorectal carcinoma: a narrative review.
Review in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Phytochemical Characterization and Antioxidant/Antitumoral Potential of Coffee Silverskin: Comparative Insights with Green and Roasted Coffee.Foods (Basel, Switzerland) · 2026Article
- Carboxymethylated β-glucan from Pichia kudriavzevii M16: structural characterization and multifunctional bioactivity.Folia microbiologica · 2026Article
- Fungi and colorectal cancer: from dysregulation to clinical translation.Gut pathogens · 2026Review
- Fiber: A New Myeloma Prevention Approach with Abundant Positive Effects.Cancer discovery · 2026Article
- The Impact of Diet on Long-Term Oncological Outcomes: Investigating Nutritional Mechanisms in Cancer Prevention Management and Prognosis.Nutrients · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDietary fiber has emerged as a preventive and adjuvant therapy for patients with colorectal carcinoma (CRC) because it possesses chemoprotective and direct anticancer properties, including the ability to modulate multiple cellular and molecular targets implicated in tumor cell survival, proliferation, invasion, angiogenesis, and immunomodulation. This review summarizes the latest epidemiological, preclinical, and clinical research on dietary fiber as a preventive and adjuvant therapy for CRC patients, focusing on the cellular and molecular mechanisms of the bioactive compounds present in or produced by fiber metabolism. MATERIALS AND
methodsA structured literature search was conducted in PubMed using a Boolean search strategy to identify relevant studies on the association between dietary fiber and CRC. Studies unrelated to dietary fiber or CRC, non-peer-reviewed materials, and articles with insufficient methodological details were excluded to maintain the focus and quality of the review.
resultsAn overall body of epidemiological evidence suggests that the consumption of foods rich in dietary fiber or whole grains is associated with a reduced risk of CRC. Preclinical studies conducted
conclusionsAccording to the current evidence, dietary fiber appears to have a protective effect against the development of CRC. However, more targeted and prospectively planned RCTs using standardized dosages, formulations and combinations of dietary fiber are needed to provide additional evidence in favor of the recommendation of a high-fiber diet for the prevention and adjuvant treatment of CRC.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.