Evidence map›Paper›PMID 41249364›Full record

ArticleScientific reports2025

Cardiopulmonary risk in the COPD patient: the EPOCONSUL audit.

Myriam Calle Rubio, Marc Miravitlles, José Luis López-Campos, Juan José Soler-Cataluña, Bernardino Alcázar-Navarrete, Manuel E Fuentes Ferrer, Juan Luis Rodríguez Hermosa

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Myriam Calle RubioPulmonology Department, Department of Medicine, School of Medicine, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain. mcallerubio@gmail.com.
Marc MiravitllesCIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
José Luis López-CamposCIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Juan José Soler-CataluñaCIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Bernardino Alcázar-NavarreteCIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Manuel E Fuentes FerrerUnidad de Investigación, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Santa Cruz de Tenerife, Spain.
Juan Luis Rodríguez HermosaPulmonology Department, Department of Medicine, School of Medicine, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Having cardiovascular disease associated with COPD is important, as it increases the risk of adverse cardiopulmonary events. to evaluate the characteristics of COPD patients with cardiovascular disease (CVD) and the therapeutic measures adopted for COPD at the follow-up visit according to COPD clinical control. A is a cross-sectional study with prospective recruitment. This analysis used data from the EPOCONSUL audit, which evaluated outpatient care provided to COPD patients in respiratory clinics in Spain. 4225 patients from 45 hospitals in Spain were audited. Cardiovascular disease was defined as having a diagnosis of active cardiovascular disease. The clinical control of COPD was defined by the criteria established in the Spanish COPD Guidelines (GesEPOC), measured by the RADAR Score, which assesses the clinical impact and stability of COPD. The COPD risk was defined according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification and GesEPOC criteria based on the degree of dyspnea, history of exacerbations, and degree of airflow obstruction. 1562 (37%) patients had CVD, with the frequency increasing in high-risk COPD according to GesEPOC (42.3%) and in type E GOLD (43.4%). Factors associated with having CVD were age ≥ 55 years as a predictor [2.46 (1.60-3.78), p<0.001], being male [1.88 (1.47-2.39), p<0.001], history of at least one hospitalization for COPD in the previous year [1.82 (1.44-2.30), p<0.001], having sleep apnoea [1.62 (1.20-2.20), p = 0.002], dyspnea (MRC-m) ≥ 2 [1.54 (1.26-1.90), p<0.001] and Charlson index without cardiovascular disease ≥ 3 [1.16 (1.09-1.24), p<0.001]. In patients with CVD, poor control of COPD was more frequent (with CVD: 44.2%; without CVD: 29.1%, p < 0.001). Closer follow-up was more frequent in patients with CVD (follow-up visits < 6 months in CVD: 44.5% vs. without CVD: 38.6%, p < 0.001). Changes in COPD treatment during the visit were more frequent in patients with poor control (in 37.8%) vs. good control (in 20.3%), p < 0.001. Cardiovascular disease was common, present in almost half of high-risk COPD patients. Poor clinical control of COPD was more common in patients with CVD, with triple therapy being the most commonly used pharmacological strategy. No differences were observed in the measures taken during the visit, nor in the request for tests or changes made to COPD treatment based on having active CVD associated with COPD. It is urgent and necessary to promote an integrated approach to improve identification and management of cardiopulmonary risk in COPD patients.

Indexed as

Cardiovascular DiseasesPulmonary Disease, Chronic ObstructiveAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsSpainCardiovascular diseaseCardiovascular risk factorsChronic obstructive pulmonary diseaseClinical controlClinical guidelines

Identifiers

PMID41249364
PMCPMC12623991

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.