Evidence mapPaperPMID 41249487Full record

ArticleNPJ digital medicine2025

Development of a deep learning-based prediction model for postoperative delirium using intraoperative electroencephalogram in adults.

Jang Ho Ahn, Hyeonhoon Lee, Pedro Gambus, Hyun-Kyu Yoon, Jae-Woo Ju, Hyung-Chul Lee

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Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jang Ho Ahn *Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
Hyeonhoon Lee *Healthcare AI Research Institute, Seoul National University Hospital, Seoul, South Korea.
Pedro GambusAnesthesiology Department, Hospital Clinic de Barcelona, and Institut d'Investigacions Biomèdiques Agusti Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Hyun-Kyu YoonDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
Jae-Woo JuDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
Hyung-Chul LeeDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea. vital@snu.ac.kr.

Funding

Korea Health Industry Development Institute RS-2024-00439677Ministry of Science and ICT, South Korea RS-2024-00441407Seoul National University Hospital 04-2023-0620
6 · The paper itself

Abstract

Postoperative delirium (POD) is associated with increased morbidity and mortality. This study aims to develop a deep learning-based model (DELPHI-EEG) to predict postoperative delirium using intraoperative electroencephalogram (EEG) waveform. A total of 34,550 surgical cases (267 event cases), with 6-lead intraoperative EEG monitoring between 2022 and 2024, were included for model development. During 5-fold cross-validation, the DELPHI-EEG model showed an area under the receiver operating characteristic (AUROC) curve of 0.870 (95% confidence interval [CI]: 0.789-0.935) and the area under the precision-recall curve (AUPRC) of 0.038 (95% CI: 0.017-0.084), significantly outperforming the logistic regression model using burst suppression ratio with AUROC of 0.729 (95% CI: 0.624-0.825, p = 0.004) and AUPRC of 0.013 (95% CI: 0.007-0.026, p = 0.002). The DELPHI-EEG model might serve as a risk predictor for postoperative delirium, potentially enabling targeted preventive interventions for surgical patients; nonetheless, external validation in diverse clinical settings is required.

Identifiers

PMID41249487
PMCPMC12623934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.