Evidence map›Paper›PMID 41249523›Full record

SynthesisAesthetic plastic surgery2026

Aesthetic Medicine in Oncology: A Systematic Review of Botulinum Toxin, Dermal Fillers, Chemical Peels, and Laser Therapies in Cancer Patient.

Mauro Barone, Beniamino Brunetti, Roberta D'Emilio, Maria Grazia Caputo, Stefania Tenna, Paolo Persichetti

Abstract readSystematic ReviewReview
PubMed Publisher
In one paragraph

Synthesis in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mauro BaroneFondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Roma, Italy. drmaurobarone@gmail.com.ORCID 0000-0002-1439-5686
Beniamino BrunettiFondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Roma, Italy.
Roberta D'Emilio, Rome, Italy.
Maria Grazia Caputo, Rome, Italy.
Stefania TennaFondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Roma, Italy.
Paolo PersichettiFondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Roma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvancements in oncology have significantly improved survival rates, shifting the focus toward enhancing the quality of life (QoL) of cancer survivors. Aesthetic medicine, encompassing procedures such as botulinum toxin injections, dermal fillers, chemical peels, and laser therapy, offers potential benefits in addressing the physical and psychological sequelae of cancer and its treatments.

objectiveTo systematically review the literature on the indications, contraindications, pharmacological interactions, and psychological impacts of aesthetic treatments in cancer patients.

methodsA comprehensive search of PubMed was conducted for studies published between January 2018 and June 2025. Inclusion criteria encompassed clinical trials, observational studies, and reviews focusing on the use of botulinum toxin, hyaluronic acid and calcium hydroxylapatite fillers, chemical peels, and laser therapy in oncology patients. Data on pharmacological interactions and psychological outcomes were also extracted.

resultsForty-two studies met the inclusion criteria. Botulinum toxin was found to be effective in managing post-treatment deformities and improving QoL in breast cancer patients. Hyaluronic acid and calcium hydroxylapatite fillers were effective in correcting post-surgical scars, with minimal adverse effects. Chemical peels demonstrated efficacy in treating actinic keratoses and precancerous lesions. Laser therapy showed promise in reducing radiation-induced dermatitis and improving skin appearance. However, certain chemotherapeutic agents posed contraindications due to potential interactions and compromised healing. Psychological benefits included improved self-esteem and body image, contributing to better overall QoL.

conclusionAesthetic treatments can be safely and effectively integrated into the care of cancer patients, with careful consideration of individual treatment regimens and potential contraindications. Further research is warranted to establish standardized guidelines. LEVEL OF EVIDENCE II: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors   www.springer.com/00266 .

Indexed as

Botulinum ToxinsChemexfoliationCosmetic TechniquesDermal FillersLaser TherapyNeoplasmsEstheticsFemaleHumansHyaluronic AcidQuality of LifeTreatment OutcomeBotulinum ToxinsDermal FillersHyaluronic AcidAesthetic medicineCosmetic medicineOncologyReview

Identifiers

PMID41249523

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.