Evidence mapPaperPMID 41249539Full record

GuidelineSurgical endoscopy2025

SAGES 2025 guidelines for fluorescence image-guided gastrointestinal surgery using indocyanine green.

Elisa C Calabrese, Sunjay Kumar, Dena Shehata, Panagiotis Kapsampelis, Stefan Scholz, María Rita Rodríguez-Luna, Nisha Narula, Jeffrey Chiu, Farah Husain, Patricia Sylla and 5 more

Abstract readSystematic ReviewPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Elisa C CalabreseDepartment of Surgery, University of California-East Bay, 1411 E 31st St, Oakland, CA, 94602, USA. eclbrs@gmail.com.ORCID http://orcid.org/0009-0007-0217-7933
Sunjay KumarDepartment of Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Dena ShehataDepartment of Surgery, Lahey Hospital and Medical Center, Burlington, MA, USA.
Panagiotis KapsampelisLeeds Institute of Emergency General Surgery, St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Stefan ScholzDivision of General and Thoracic Pediatric Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
María Rita Rodríguez-LunaDepartment of General Surgery, Hospital de Barcelona, Barcelona, Spain.
Nisha NarulaDepartment of Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA.
Jeffrey ChiuDepartment of General Surgery, Advent Health, Orlando, FL, USA.
Farah HusainDepartment of Surgery, University of Arizona College of Medicine, Phoenix, AZ, USA.
Patricia SyllaIcahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.
Guy MaddernDepartment of Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, SA, Australia.
Subhashini AylooDepartment of Surgery, Saginaw VA Health Care System, Saginaw, MI, USA.
Ziad AwadDepartment of Surgery, University of Florida College of Medicine, Jacksonville, FL, USA.
Bethany J SlaterMount Sinai Kravis Children's Hospital, New York, NY, USA.
Deborah S KellerDivision of Digestive Surgery, University of Strasbourg, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluorescence image-guided surgery (FIGS) with indocyanine green (ICG) is a surgical adjunct that provides real-time, advanced visualization during surgery. It has been increasingly used in clinical practice for its potential to enhance intraoperative precision and safety. However, evidence to date regarding its utility remains variable. An expert panel was convened to provide evidence-based recommendations on the intraoperative use of FIGS with ICG across several surgical applications to support clinicians and patients in decision-making. METHODOLOGY: A systematic review was carried out, including a literature search up to October 2022, addressing eight key questions regarding FIGS with ICG compared to its absence in various surgical settings and service lines. The findings were subsequently presented to a panel of adult and pediatric surgeons. Subject matter experts then used the GRADE methodology to develop evidence-based recommendations.

resultsRecommendations in favor of using FIGS with ICG were made for detection of non-regional metastases, intraoperative identification of primary cancers, LN identification in GI cancers, and anastomosis quality in esophageal and left-sided colorectal anastomosis. Thoracic duct identification and bariatric and pediatric pull-through anastomosis did not have sufficient evidence to make a formal recommendation. Still, the expert consensus was that FIGS with ICG is a reasonable option for those surgical applications.

conclusionThese recommendations guide the use of FIGS with ICG in different surgical areas according to the existing literature and expert input. The panel also highlighted evidence gaps to support future research for a stronger evidence base around FIGS in adult and pediatric gastrointestinal surgery.

Indexed as

Digestive System Surgical ProceduresGastrointestinal NeoplasmsIndocyanine GreenOptical ImagingSurgery, Computer-AssistedColoring AgentsHumansColoring AgentsIndocyanine GreenFluorescence image-guided surgery (FIGS)Fluorescent imagingGastrointestinal (GI) surgeryGuidelinesIndocyanine green (ICG)

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.