Evidence map›Paper›PMID 41249546›Full record

ReviewCommunications biology2025

The role of extremophile microbiomes in terraforming Mars.

Claudia Coleine, Manuel Delgado-Baquerizo, Alexandre S Rosado, Andrea Zerboni

Abstract readReview
In one paragraph

Review in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Claudia ColeineDepartment of Ecological and Biological Sciences, University of Tuscia, Viterbo, Italy. cla.coleine@gmail.com.ORCID http://orcid.org/0000-0002-9289-6179
Manuel Delgado-BaquerizoLaboratorio de Biodiversidad y Funcionamiento Ecosistémico. Instituto de Recursos Naturales y Agrobiología de Sevilla (IRNAS), Consejo Superior de Investigaciones Científicas (CSIC), Sevilla, Spain.ORCID http://orcid.org/0000-0002-6499-576X
Alexandre S RosadoDivision of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.ORCID http://orcid.org/0000-0001-5135-1394
Andrea ZerboniDipartimento di Scienze della Terra "A. Desio", Università degli Studi di Milano, Milano, Italy.ORCID http://orcid.org/0000-0002-6844-8528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Terraforming Mars toward sustainable life-supporting ecosystems poses unprecedented challenges. Extremophilic microbes, which thrive in Earth's most extreme environments, offer promising biological strategies for initial Mars colonization providing tools for resource mobilization and atmospheric engineering. This review synthesizes experimental evidence on microbial survival Mars-simulated conditions, highlights the ecological roles of extremophilic microbial consortia in biogeochemical cycling. We further discuss cutting-edge synthetic biology approaches to enhance microbial resilience. Yet, we emphasize the need to shift focus from single-species assessments to complex, synergistically interacting microbial communities, which may hold the key to establishing self-sustaining extraterrestrial biospheres. Finally, we consider planetary protection, ethical concerns, and future research priorities to responsibly perform Mars terraforming.

Indexed as

Extraterrestrial EnvironmentExtremophilesMarsMicrobiotaArchaeaAtmosphereBacteriaFungi

Identifiers

PMID41249546
PMCPMC12623876

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.