ReviewClinical and experimental medicine2025
A symphony of signals: the intricate role of lncRNAs in dermatological disorders.
Review in Clinical and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Molecular Pathogenesis of Vitiligo: Emerging Roles of Epigenetic Regulation.Biomolecules & therapeutics · 2026Review
- Harnessing the LncRNA CCAT2 role in gastric cancer: from molecular insights to clinical implications.Cancer cell international · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The skin, as the body's largest organ, relies on complex molecular networks to maintain homeostasis and repair damage. Recent advances in genomic research have highlighted the significance of long non-coding RNAs (lncRNAs), transcripts longer than 200 nucleotides, which act as key regulators of gene expression rather than mere transcriptional byproducts. Growing evidence suggests that lncRNAs influence critical signaling pathways, including PI3K/AKT/mTOR, Wnt/β-catenin, NF-κB, JAK/STAT, and TGF-β/SMAD shaping both normal skin biology and disease processes. This review synthesizes current knowledge on how to regulate the pathogenesis of dermatological conditions, including atopic dermatitis, psoriasis, vitiligo, systemic sclerosis, melanoma, and others. By outlining their potential roles as biomarkers and therapeutic targets, this work underscores the novelty and clinical relevance of lncRNA research in dermatology.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.