Evidence map›Paper›PMID 41249847›Full record

ArticleInternational journal of obesity (2005)2026

The Physiology Of the WEight Reduced State (POWERS) study: assessing energy balance.

Michael Rosenbaum, Kelly C Allison, Maren R Laughlin, Kathryn Whyte, John M Jakicic, Laurel E S Mayer, Maxine Ashby-Thompson, Matthew R Hayes, John Speakman, Rudolph L Leibel and 4 more

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Michael Rosenbaum *Department of Pediatrics, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-2835-9202
Kelly C Allison *Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. kca@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0002-9807-0220
Maren R LaughlinDivision of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
Kathryn WhyteDepartment of Pediatrics, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, NY, USA.
John M JakicicDepartment of Internal Medicine, Division of Physical Activity and Weight Management, University of Kansas Medical Center, Kansas City, KS, USA.ORCID http://orcid.org/0000-0001-6800-9368
Laurel E S MayerDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.
Maxine Ashby-ThompsonDepartment of Pediatrics, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-9752-2208
Matthew R HayesDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-9782-6551
John SpeakmanSchool of Biological Sciences, University of Aberdeen, Aberdeen, UK.ORCID http://orcid.org/0000-0002-2457-1823
Rudolph L LeibelDepartment of Pediatrics, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-6062-7222
Sai Krupa DasEnergy Metabolism Team, Jean Mayer USDA Human Nutrition Research Center on Aging, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Medford, MA, USA.ORCID http://orcid.org/0000-0003-0788-0461
Dympna GallagherDivision of Endocrinology, New York Nutrition Obesity Research Center, Department of Medicine, Columbia University, New York, NY, USA.
Susan B RobertsDartmouth College Geisel School of Medicine, Hanover, NH, USA.ORCID http://orcid.org/0000-0003-1320-8460
POWERS Consortium

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Thomas Glenn Travison · 2008 to 2026
$23.9M
Predictors of Recidivism to Obesity in Weight-Reduced IndividualsUH3DK128302 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DYMPNA GALLAGHER, RUDOLPH L LEIBEL · 2022 to 2026
$7.0M
Predicting Weight Regain Following Weight Loss Using Physiological Measures of Appetite and Energy ExpenditureUH3DK128298 · NIDDK · DREXEL UNIVERSITY · PI KELLY C ALLISON, MATTHEW R HAYES · 2022 to 2026
$6.8M
The Physiology of the Weight Reduced State Data Coordinating CenterU24DK128125 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Steven H. Belle, Maria Mori Brooks · 2021 to 2026
$4.9M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
Interpretable graphical models for large multi-modal COPD data (R01HL159805)R01HL159805 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENOS, PANAGIOTIS V, SPIRTES, PETER · 2021 to 2024
$2.0M
Support Mentoring of Early Career Clinical Researchers from Diverse BackgroundsK26DK138418 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DYMPNA GALLAGHER · 2023 to 2026
$483k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR001878NHLBI NIH HHS R01 HL159805NIA NIH HHS P30 AG031679NIDDK NIH HHS K26 DK138418NIDDK NIH HHS P30 DK026687NIDDK NIH HHS T32 DK007559NIDDK NIH HHS U24 DK128125NIDDK NIH HHS UH3 DK128298NIDDK NIH HHS UH3 DK128302
6 · The paper itself

Abstract

BACKGROUND/

objectivesWe provide the rationale for and description of energy balance measures (i.e., energy intake and energy expenditure) in The Physiology Of the WEight Reduced State (POWERS) study which aims to understand the contribution of the many factors that influence weight regain following behavioral weight loss.

methodsThe primary dependent variable is weight regain over 1 year following a 7% or greater supervised weight loss. The balance between energy intake and expenditure is the primary determinant of weight regain. Healthy adults (target n = 205), aged 25- < 60 years, with body mass index (BMI) 30- < 40 kg/m DISCUSSION: This manuscript describes the rationale for the methods chosen to assess energy balance and the analytical methods employed to normalize and express data in the setting of changes in body weight and composition immediately following behavioral weight loss and thereafter at 4- and 12-months post-weight loss.

Indexed as

Energy IntakeEnergy MetabolismObesityWeight GainWeight LossAbsorptiometry, PhotonAdultBody CompositionBody Mass IndexFemaleHumansMaleMiddle Aged

Identifiers

PMID41249847
PMCPMC13147300

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.