Evidence map›Paper›PMID 41250600›Full record

ArticleGut microbes2025

Proteome profiling indicates a link between mitochondrial pathways and the host-microbial sensor ELMO1 following

Sajan C Achi, Dominic McGrosso, Stefania Tocci, Isaac Amao, Baibaswata Saha, Stella-Rita Ibeawuchi, Ibrahim M Sayed, David J Gonzalez, Soumita Das

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sajan C AchiDepartment of Biomedical and Nutritional Sciences, University of Massachusetts - Lowell, Lowell, MA, USA.
Dominic McGrossoDepartment of Pharmacology, University of California, San Diego, CA, USA.
Stefania TocciDepartment of Biomedical and Nutritional Sciences, University of Massachusetts - Lowell, Lowell, MA, USA.
Isaac AmaoDepartment of Biomedical and Nutritional Sciences, University of Massachusetts - Lowell, Lowell, MA, USA.
Baibaswata SahaDepartment of Biomedical and Nutritional Sciences, University of Massachusetts - Lowell, Lowell, MA, USA.
Stella-Rita IbeawuchiDepartment of Pathology,University of California, San Diego, CA, USA.
Ibrahim M SayedDepartment of Biomedical and Nutritional Sciences, University of Massachusetts - Lowell, Lowell, MA, USA.
David J GonzalezDepartment of Pharmacology, University of California, San Diego, CA, USA.
Soumita DasDepartment of Biomedical and Nutritional Sciences, University of Massachusetts - Lowell, Lowell, MA, USA.ORCID 0000-0003-3895-3643

Funding

NIA NIH HHS R56 AG069689NIDDK NIH HHS R01 DK107585
6 · The paper itself

Abstract

The host EnguLfment and cell MOtility protein 1 (ELMO1) is a cytosolic microbial sensor that binds bacterial effector proteins, including pathogenic effectors from

Indexed as

Adaptor Proteins, Signal TransducingMitochondriaProteomeSalmonella InfectionsSalmonella typhimuriumAnimalsCell LineDynaminsHost-Pathogen InteractionsMacrophagesMiceMitochondrial ProteinsProteomicsAdaptor Proteins, Signal TransducingDnm1l protein, mouseDynaminsMitochondrial ProteinsProteomebacterial effectorDRP1ELMO1macrophagesMicrobial sensormitochondrial dynamicsmitochondrial fissionproteomicsSifA

Identifiers

PMID41250600
PMCPMC12629339

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.