Evidence map›Paper›PMID 41250913›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits.

Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Characterization ofFrontiers in plant science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Huifang XuState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Shiyu HuangState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Jie WangState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Tian WangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Life Sciences, Northwest A&F University, Yangling, 712100, China.
Qingqing HanState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Kexin WuState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Zhen GaoState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Xiaolei ShiHebei Laboratory of Crop Genetics and Breeding, Institute of Cereal and Oil Crops, Hebei Academy of Agricultural and Forestry Sciences, Shijiazhuang, 050035, China.
Tianli TuState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Ming WangState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Laimei HuangState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Jiaomei ChenState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Yunqi LiuZhongguancun Xuyue Non-invasive Micro-test Technology Industrial Alliance, Beijing, 10080, China.
Yumei ZhangInstitute of Crops, Fujian Academy of Agricultural Sciences, Fuzhou, 350013, China.
Guoqiang LinInstitute of Crops, Fujian Academy of Agricultural Sciences, Fuzhou, 350013, China.
Zhichang ChenState Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing, 211135, China.
Xu ChenState Key Laboratory of Agricultural and Forestry Biosecurity, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.ORCID https://orcid.org/0000-0002-5166-083X

Funding

Funding for a World-Class Plant Protection Discipline 133-725025010BJoint Research Program of State Key Laboratory of Agricultural and Forestry Biosecurity SKLJPR2505National Key Research, Development Program of China 2022YFA0912100National Natural Science Foundation of China -Youth Fund Project 32300277National Natural Science Foundation-Outstanding Youth Foundation 32222009Natural Science Foundation of Fujian 2022J01161Natural Science Foundation of Fujian 2023J01482
6 · The paper itself

Abstract

Enhancing nitrogen-use efficiency is essential for boosting crop yields and advancing sustainable agriculture, particularly in the absence of synthetic fertilizers. Despite the inherent nitrogen-fixation capacity of the staple legume crop soybean (Glycine max) by symbiotic rhizobia, improving nitrogen use has been challenging. Here, a role for the auxin-efflux transporters PIN3a and PIN3b in soybean nitrate acquisition is uncovered. PIN3a/b localizes to the plasma membrane, and high environmental nitrate induces PIN3a degradation and its accumulation at cell junctions. Disrupting PIN3 homologs results in auxin over-accumulation, impairs pavement-cell polarity, and enhances signaling via the transcription factors ARF and STF3/4. These transcription factors separately bind to and activate the NPF2.13 promoter, thereby strengthening nitrate uptake. pin3ab and pin3abd mutants have enhanced nitrate acquisition and resistant to high nitrate on pavement-cell growth. The elevated nitrogen accumulation translates to higher oil contents in pin3ab mutant seeds in an elite cultivar background across multiple years and field locations. The findings shed light on the regulation of nitrate uptake in crop-plant development and demonstrate the unexpected potential of manipulating auxin transporters to enhance soybean nitrogen-use efficiency and agronomic performance.

Indexed as

Glycine maxIndoleacetic AcidsNitratesNitrogenPlant ProteinsSeedsGene Expression Regulation, PlantIndoleacetic AcidsNitratesNitrogenPlant Proteinsauxinleaf developmentnitratePIN3seed oilsoybean

Identifiers

PMID41250913
PMCPMC12948193

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.