Evidence map›Paper›PMID 41251344›Full record

ArticleJournal of virology2025

TRIM47 inhibits murine norovirus replication in a strain-dependent manner.

Stacey L Crockett, Linley R Pierce, Rachel Rodgers, Meagan Sullender, Lawrence A Schriefer, Mridula Annaswamy Srinivas, Sanghyun Lee, Megan T Baldridge, Robert C Orchard

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stacey L CrockettDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Linley R PierceDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Rachel RodgersDivision of Infectious Diseases, Department of Medicine, Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.
Meagan SullenderDivision of Infectious Diseases, Department of Medicine, Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.
Lawrence A SchrieferDivision of Infectious Diseases, Department of Medicine, Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.
Mridula Annaswamy SrinivasDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Sanghyun LeeDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-0736-1648
Megan T BaldridgeDivision of Infectious Diseases, Department of Medicine, Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-7030-6131
Robert C OrchardDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-8216-4946

Funding

INTEGRATIVE IMMUNOLOGY TRAINING PROGRAMT32AI005284 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Nan Yan · 2003 to 2026
$7.4M
The Role of Trim Proteins in Regulating Norovirus Replication and TropismR01DK133231 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Robert C. Orchard · 2023 to 2026
$1.9M
Viral immune evasion during intestinal norovirus infectionR01AI183155 · NIAID · BROWN UNIVERSITY · PI Sanghyun Lee · 2024 to 2026
$1.7M
NIAID NIH HHS R01 AI183155NIAID NIH HHS T32 AI005284NIDDK NIH HHS R01 DK133231
6 · The paper itself

Abstract

Human norovirus is the leading cause of gastroenteritis worldwide. Norovirus exhibits remarkable genetic diversity. Understanding the impact of genetic diversity on infection and immunity has been challenging due to the difficulties in

Indexed as

Caliciviridae InfectionsNorovirusTripartite Motif ProteinsVirus ReplicationAnimalsCell LineGastroenteritisGenetic VariationHost-Pathogen InteractionsHumansMiceViral Nonstructural ProteinsTripartite Motif ProteinsViral Nonstructural Proteinsmurine norovirusnorovirusTrim47

Identifiers

PMID41251344
PMCPMC12692738

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.