Trial reportJournal of acquired immune deficiency syndromes (1999)2026
PrEP and Contraceptive Persistence Among Young Women Receiving Sexual and Reproductive Health Services Through Hair Salons in South Africa.
Trial report in Journal of acquired immune deficiency syndromes (1999), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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14 authors.
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Abstract
backgroundYoung women have high HIV incidence and risk for unintended births in sub-Saharan Africa. Hair salons may be useful settings for HIV prevention and family planning. We assessed PrEP and contraceptive persistence in South African hair salons.
methodsWe conducted a pilot randomized trial to evaluate uptake and persistence of pre-exposure prophylaxis (PrEP) and contraception in 3 salons in KwaZulu-Natal. Women could start or stop medication at any visit. We defined persistence as 1 additional visit within 6 months with continued use. We assessed age, self-perceived HIV risk, partner 5 years older, primary partner having other partners, intimate partner violence, STI at enrolment, contraception persistence, mental health, and alcohol use using contingency tables.
resultsAmong 159 intervention participants, the median age was 26 years (IQR 22-29). Thirty-five (26%) were HIV positive, and 42/158 (27%) were using contraception at enrolment. 32/111 (29%) described at least moderate HIV risk in the following year, and 46/142 (32%) reported partners with other partners. 63/124 (51%) accepted PrEP; among 60 with follow-up data, 32 (53%) persisted. 138/159 (87%) took contraception; among 134 with follow-up data, 95 (71%) persisted. Persistence on PrEP was associated with age 25 and older (RR: 1.83 [95% CI: 1.03 to 4.00]), alcohol use (RR: 1.68 [95% CI: 1.03 to 2.92]), partner concurrency (RR: 0.49 [95% CI: 0.14 to 0.95]), and contraceptive persistence (RR: undefined).
conclusionsWomen accepted PrEP and contraception through hair salons, with contraception persistence higher than PrEP. PrEP persistence was associated with age, alcohol use, partner concurrency, and contraceptive persistence. Hair salons are a novel venue for service delivery.
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