Evidence map›Paper›PMID 41253826›Full record

ArticleNature communications2025

Cu/Zn/histidine supramolecular assemblies with optimized Cu catalytic sites as an alternative of superoxide dismutase.

Hao Jin, Xuanqi Zhu, Mengsi Zhang, Hao Zheng, Yang Chen, Dong Yao, Shuwei Liu, Hao Zhang

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao JinState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, P. R. China.
Xuanqi ZhuState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, P. R. China.
Mengsi ZhangInstitute of Translational Medicine, The First Hospital of Jilin University, Changchun, P. R. China.
Hao ZhengState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, P. R. China.
Yang ChenState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, P. R. China.
Dong YaoInstitute of Theoretical Chemistry, College of Chemistry, Jilin University, Changchun, P. R. China.ORCID http://orcid.org/0000-0003-4594-3515
Shuwei LiuInstitute of Translational Medicine, The First Hospital of Jilin University, Changchun, P. R. China. liushuwei@jlu.edu.cn.
Hao ZhangState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, P. R. China. hao_zhang@jlu.edu.cn.ORCID http://orcid.org/0000-0002-2373-1100

Funding

Department of Science and Technology of Jilin Province (Jilin Province Science and Technology Department) SKL202302001National Natural Science Foundation of China (National Science Foundation of China) 52303085
6 · The paper itself

Abstract

Superoxide dismutase (SOD), featured with unique metal catalytic sites, is the first defense against reactive oxygen species (ROS) damage in vivo and well used in the treatment of oxidative stress-related diseases. However, the catalytic activity of natural SOD is limited by the metal ion coordination with rigid amino-acid residues. Inspired by the Cu

Indexed as

CopperHistidineSuperoxide DismutaseZincAnimalsCatalysisCatalytic DomainHumansMacrophagesMaleMiceOxidative StressReactive Oxygen SpeciesCopperHistidineReactive Oxygen SpeciesSuperoxide DismutaseZinc

Identifiers

PMID41253826
PMCPMC12627631

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.