Evidence mapPaperPMID 41254237Full record

SynthesisCardiovascular and interventional radiology2026

Lumbar Sympathectomy in Chronic Limb-Threatening Ischaemia: Current Trends and Future Directions.

Yusuf H Wardak, Yun-En Chung, Hong Kuan Kok, Goran Mitreski

Abstract readReviewSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yusuf H WardakUniversity of Melbourne, Melbourne, Australia. ywardak@student.unimelb.edu.au.ORCID http://orcid.org/0009-0009-5709-5972
Yun-En ChungUniversity of Melbourne, Melbourne, Australia.
Hong Kuan KokInterventional Radiology Service, Northern Health, Northern Imaging Victoria, Melbourne, Australia.
Goran MitreskiInterventional Radiology Service, Northern Health, Northern Imaging Victoria, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lumbar sympathectomy (LS) remains a therapeutic option for patients with chronic limb-threatening ischaemia not amenable to revascularisation. A systematic review was performed with sixteen total studies included. Retroperitoneoscopic LS was safer than open LS, with a shorter hospital stay. Chemical LS showed comparable efficacy with fewer complications and a reduced admission time. Irrespective of modality, LS provided consistent pain relief, wound healing, and quality-of-life improvement, though haemodynamic improvements were inconsistent. Limb salvage rates were generally favourable with no procedure-associated mortality. LS remains a niche, palliative intervention that may offer meaningful symptomatic relief when revascularisation is not feasible. Further long-term prospective studies measuring key haemodynamic parameters are required to refine patient selection and ascertain the potential of LS in modern chronic limb-threatening ischaemia management.

Indexed as

IschemiaSympathectomyChronic DiseaseHumansTreatment OutcomeChemical lumbar sympathectomy (CLS)Chronic limb-threatening ischaemia (CLTI)Conventional open lumbar sympathectomy (COLS)Lumbar sympathectomy (LS)Peripheral arterial disease (PAD)Retroperitoneoscopic lumbar sympathectomy (RPLS)

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.