Evidence map›Paper›PMID 41255123›Full record

Trial reportObesity (Silver Spring, Md.)2026

The Influence of Ultraprocessed Food Consumption on Energy Intake in Emerging Adulthood: A Controlled Feeding Trial.

Maria L M Rego, Emma Leslie, Emily Schmall, Bailey Capra, Summer Hudson, Monica L Ahrens, Benjamin Katz, Kevin P Davy, Valisa E Hedrick, Alexandra G DiFeliceantonio and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05550818 (Influence of Ultra-processed Foods on Reward Processing and Energy Intake), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05550818 nacompletednot on this map

Influence of Ultra-processed Foods on Reward Processing and Energy Intake

TypeinterventionalSponsorVirginia Polytechnic Institute and State UniversityRan2023 to 2025Enrolled36ConditionsEating Behavior, Eating HabitArmsHigh Ultra Processed Food Diet, No Ultra Processed Food Diet
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria L M RegoDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.ORCID https://orcid.org/0000-0003-4218-8999
Emma LeslieFralin Biomedical Research Institute, Virginia Tech, Roanoke, Virginia, USA.
Emily SchmallDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.
Bailey CapraDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.
Summer HudsonDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.
Monica L AhrensDepartment of Statistics, Virginia Tech, Blacksburg, Virginia, USA.
Benjamin KatzDepartment of Human Development and Family Science, Virginia Tech, Blacksburg, Virginia, USA.
Kevin P DavyDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.
Valisa E HedrickDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.
Alexandra G DiFeliceantonioDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.ORCID https://orcid.org/0000-0002-7155-6060
Brenda M DavyDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.

Funding

NICHD NIH HHS R21 HD109722NIH HHS R21HD109722
6 · The paper itself

Abstract

objectiveThis study examined the impact of a 2-week eucaloric diet high in ultraprocessed foods (UPF) compared to a diet without UPF (non-UPF) on ad libitum energy intake (EI) and food selection in individuals aged 18-25.

methodsIn a randomized, crossover, proof-of-concept trial, participants completed two 14-day controlled feeding periods (81% UPF vs. 0% UPF), with a 4-week washout. Diets were matched for macronutrients, fiber, added sugar, diet quality, and energy density. Following each condition, participants consumed an ad libitum buffet meal including UPF and non-UPF. Energy and food grams consumed were quantified. Statistical analyses were conducted for the full sample, late adolescents (aged 18-21), and young adults (aged 22-25).

resultsTwenty-seven individuals aged 22 ± 2 years (mean BMI = 24 ± 3 kg/m

conclusionsLate adolescents may be susceptible to increased EI following a UPF diet. Future trials are warranted to evaluate this possibility.

trial registrationClinicalTrials.gov: NCT05550818.

Indexed as

DietEnergy IntakeFast FoodsFeeding BehaviorFood HandlingAdolescentAdultCross-Over StudiesEatingFemaleFood PreferencesHumansMaleYoung Adulteating behaviorsenergy intakeultraprocessed foods

Identifiers

PMID41255123
PMCPMC12850616

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.