ReviewMaterials today. Bio2025
Innovative biomaterials in promoting intraoral wound healing: Mechanisms, applications, and challenges.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07367165 (Improving Palatal Donor Site Healing and Reducing Postoperative Morbidity With Concentrated Growth Factor and Collagen Fleece), which is not on this map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Palatal Donor Site Healing and Reducing Postoperative Morbidity With Concentrated Growth Factor and Collagen Fleece: Randomized Controlled Clinical Study
Who cites it
6 citing papers in PubMed.
- An injectable tough hydrogel sealant enabling rapid hemostasis and promoting oral tissue regeneration.Bioactive materials · 2026Article
- Oxidative Stress Biomarkers in Oral Mucosal Wound Healing and Photobiomodulation: Biochemical Pathways, Experimental Models, and Translational Perspectives.International journal of molecular sciences · 2026Review
- Plant Exosome Injection: A New Boost for Postlaser Vascular Repair.The Journal of clinical and aesthetic dermatology · 2026Article
- Hyaluronic Acid-Based Gels and Biomaterial Systems for Oral Wound Healing: Design and Clinical Translation.Gels (Basel, Switzerland) · 2026Review
- Bioactive Hydrogels and Scaffolds for Oral Mucosal Regeneration After Oral Squamous Cell Carcinoma Therapy: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2026Review
- Evaluation of the efficacy of electrospun gelatin/polycaprolactone nanofiber membranes in repairing beagle dog buccal mucosa defects and a comparative study with acellular dermal matrix.Frontiers in bioengineering and biotechnology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intraoral wounds face unique challenges, including a humid microenvironment, mechanical stress, and microbial colonization, complicating healing. Local and systemic factors further impair regeneration. Biomaterials with tailored mechanical properties, antibacterial activity, and bioactivity show promise in promoting mucosal repair and bone regeneration. However, dynamic microenvironment adaptation and multifunctional integration remain unmet needs. This review provides an integrative overview of the latest advancements in biomaterials for intraoral wound healing. We discuss the physiological mechanisms of intraoral wound healing, key influencing factors. Additionally, we explore the idea properties of biomaterials and their applications in various intraoral wound scenarios and highlight future directions in biomaterial development to guide clinical practice and research.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.