Evidence map›Paper›PMID 41256014›Full record

ArticleMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents2025

IND-Enabling Preclinical Studies of [

Madison Frazier, Tanpreet Kaur, Jenelle Stauff, Wade P Winton, Bradford D Henderson, Alexandra S Dumond, Xia Shao, David M Raffel, Kirk A Frey, Michael R Kilbourn and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Madison FrazierDepartment of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109.
Tanpreet KaurDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Jenelle StauffDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Wade P WintonDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Bradford D HendersonDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Alexandra S DumondDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Xia ShaoDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
David M RaffelDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Kirk A FreyDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Michael R KilbournDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Allen F BrooksDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Peter J H ScottDepartment of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-6505-0450

Funding

Radiolabled MAO-B Substrates for ImagingR21NS075553 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KILBOURN, MICHAEL R · 2011 to 2012
$428k
Clinical MAO PET Imaging via Trapped MetabolitesR21AG073686 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FREY, KIRK A., SCOTT, PETER JAMES HENRY · 2021 to 2021
$319k
NIA NIH HHS R21 AG073686NINDS NIH HHS R21 NS075553
6 · The paper itself

Abstract

[

Indexed as

DosimetryMAO-BPET imagingPharmacology/ToxicologyPreclinical studySynthesis validation

Identifiers

PMID41256014
PMCPMC12622565

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.