Evidence map›Paper›PMID 41256827›Full record

ReviewScientifica2025

Probiotics Supplementation in Tuberculosis: A Scoping Review.

Tejaswini Baral, Mohan K Manu, Kavitha Saravu, Chandrashekar Udyavara Kudru, Jitendra Singh, Chiranjay Mukhopadhyay, Mahadev Rao, Sonal Sekhar Miraj

Abstract readReview
In one paragraph

Review in Scientifica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tejaswini BaralDepartment of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID https://orcid.org/0000-0002-6185-3600
Mohan K ManuDepartment of Respiratory Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID https://orcid.org/0000-0002-9481-3189
Kavitha SaravuDepartment of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID https://orcid.org/0000-0001-6399-1129
Chandrashekar Udyavara KudruDepartment of Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID https://orcid.org/0000-0002-8274-9677
Jitendra SinghDepartment of Translational Medicine, All India Institute of Medical Sciences, Bhopal 462020, Madhya Pradesh, India.ORCID https://orcid.org/0000-0001-5626-6076
Chiranjay MukhopadhyayDepartment of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID https://orcid.org/0000-0003-0402-1143
Mahadev RaoDepartment of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID https://orcid.org/0000-0003-3322-5399
Sonal Sekhar MirajDepartment of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID https://orcid.org/0000-0003-3660-2022

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This scoping review aims to synthesize the current clinical evidence on probiotics used in tuberculosis (TB). Systematic literature searches were conducted across PubMed, Scopus, and Embase databases to identify all studies using probiotics in TB. A total of six studies conducted between 2016 and 2023 were found and included in this review. All the studies incorporated probiotics supplementation not beyond the intensive phase of antitubercular therapy (ATT), ranging from three to eight weeks. Five out of six included studies focused on pulmonary TB. Probiotics alleviate adverse gastrointestinal and hepatic drug reactions, modulate gut microbiota, enhance barrier function, and influence immune responses. Therefore, probiotics are a potential adjunct therapy during the intensive phase of ATT. However, their long-term effects remain unexplored, highlighting the future research scope for well-designed longitudinal studies to explore their sustained benefits.

Indexed as

antitubercular therapyprobioticstuberculosis

Identifiers

PMID41256827
PMCPMC12623083

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.