ArticleBioFactors (Oxford, England)
Oleuropein Aglycone Modulates Oxidative Stress and Autophagy-Related Pathways in Human Skeletal Muscle Cells.
Article in BioFactors (Oxford, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Innovative strategies for immune thrombocytopenia treatment: immunomodulatory mechanisms and clinical potential of mesenchymal stem cells.Stem cell research & therapy · 2026Review
- Oleuropein Aglycone Modulates Oxidative Stress and Autophagy-Related Pathways in Human Skeletal Muscle Cells.BioFactors (Oxford, England)Article
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Authors and funding
4 authors.
Funding
Abstract
A gradual loss of muscle mass and strength increases the risk of falls, frailty and mortality. It is the result of a combination of intrinsic factors such as oxidative stress, mitochondrial dysfunction and extrinsic factors such as poor nutrition and inactivity. Oleuropein aglycone (OLE), a compound extracted from olive leaves, combats oxidative damage through its antioxidant and autophagy-inducing properties. It activates AMPK and FOXO3a signaling pathways, autophagy, mitochondrial function and muscle health. OLE is investigated in the human immortalized myoblast cell line AB1079 for its protective effect against muscle oxidative stress. Oxidative stress was induced in the AB1079 cell line after 7 days of differentiation by hydrogen peroxide (H
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