Evidence map›Paper›PMID 41258077›Full record

ArticleExperimental & molecular medicine2025

RNA-associated glycoconjugates highlight potential ambiguities in glycoRNA analysis.

Sungchul Kim, Zeshi Li, Yong-Geun Choi, Kirsten Janssen, Jan-Willem H Langenbach, Daan J van den Brink, Christian Büll, Bhagyashree S Joshi, Adam Pomorski, Vered Raz and 3 more

Abstract read
In one paragraph

Article in Experimental & molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Defining cell surface and glycosylated RNAs.Trends in genetics : TIG · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sungchul Kim *Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea. sungchulkim.kr@gmail.com.
Zeshi Li *Division of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands. z.li@uu.nl.
Yong-Geun ChoiCenter for RNA Research, Institute for Basic Science, Seoul, Republic of Korea.
Kirsten JanssenDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Jan-Willem H LangenbachDivision of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Daan J van den BrinkDivision of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID http://orcid.org/0009-0004-0874-5573
Christian BüllDepartment of Biomolecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0001-7785-2920
Bhagyashree S JoshiDepartment of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, The Netherlands.
Adam PomorskiDepartment of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, The Netherlands.ORCID http://orcid.org/0000-0002-0669-3421
Vered RazHuman Genetics department, Leiden University Medical Centre, Leiden, The Netherlands.ORCID http://orcid.org/0000-0003-3152-1952
Marvin E TanenbaumDepartment of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, The Netherlands.
Pascal MiesenDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands. pascal.miesen@radboudumc.nl.
Chirlmin JooDepartment of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, The Netherlands. c.joo@tudelft.nl.

Funding

EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities (2007 to 2013)) 819299Nederlandse Organisatie voor Wetenschappelijk Onderzoek (Netherlands Organisation for Scientific Research) OCENW.XS21.4.046Nederlandse Organisatie voor Wetenschappelijk Onderzoek (Netherlands Organisation for Scientific Research) VI.Veni.222.272
6 · The paper itself

Abstract

A recent ground-breaking study suggested that small RNA from mammalian cells can undergo N-glycan modifications (termed glycoRNA)

Indexed as

GlycoconjugatesRNA, Small NucleolarAnimalsGlycosylationHumansPolysaccharidesRibonucleasesGlycoconjugatesPolysaccharidesRibonucleasesRNA, Small Nucleolar

Identifiers

PMID41258077
PMCPMC12685941

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.