ReviewEuropean journal of medical research2025
The mechanism of C1q/TNF-related proteins (CTRPs) in atherosclerosis associated with type 2 diabetes mellitus.
Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Circulating CTRP1 in Adults with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Increasing evidence suggests that C1q/tumor necrosis factor-related proteins (CTRPs), as the adipokine superfamily, are secreted by adipose tissues. They play an important role in diabetic cardiovascular pathology. Diabetic vascular complications pose a significant threat to human health and are the primary cause of disability and mortality in diabetes. Adipose tissue dysfunction, including secretion and dysfunction of adipokines, is closely associated with diabetic vasculopathy. However, the expression levels of CTRPs show heterogeneity in different pathophysiological states, and their potential mechanisms of action have not been elucidated. Therefore, this review aims to summarize and discuss the differences in circulating expression of CTRPs in diabetic patients, as well as their roles and mechanisms in diabetic vasculopathy, to offer new insights and targets for the prevention and treatment of diabetic vasculopathy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.