Evidence map›Paper›PMID 41258561›Full record

ArticleDiscover oncology2025

Bibliometric analysis of global research on breast cancer with HER2-low expression.

Junpeng Zhu, Jin Hu, Hao Lei, Runze Li, Yu Zhao, Yaqi Zhao, Hengyu Chen, Lei Li, Chong Lu, Chunping Liu

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junpeng Zhu *Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Jin Hu *Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Hao Lei *Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, 570311, China.
Runze LiDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Yu ZhaoDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Yaqi ZhaoDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Hengyu ChenDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, 570311, China.
Lei LiDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. leili2008@hust.edu.cn.
Chong LuDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. lcwhxh@hust.edu.cn.
Chunping LiuDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. lcp191@163.com.

Funding

National Natural Science Foundation of China 82203147National Natural Science Foundation of China 82203813National Natural Science Foundation of China 82303861National Natural Science Foundation of China 82373055National Natural Science Foundation of China 82373144The High-level Talents Program of Hainan Province Natural Science Foundation 823RC594The Hubei Provincial Key Research and Development Program 2023BCB011
6 · The paper itself

Abstract

backgroundThe abnormal expression of Human Epidermal Growth Factor Receptor 2 (HER2) is closely related to the prognosis of breast cancer. Since the concept of HER2-low expression was introduced in 2018, researches on HER2-low expression breast cancer have burgeoned. This bibliometric analysis seeks to evaluate the worldwide distribution of literature, research focuses, and upcoming trends in HER2-low expression breast cancer research.

methodsWe extensively searched for articles on HER2-low expression breast cancer from January 2018 to March 2025 using the Web of Science database. By employing the Bibliometrix, VOSviewer and CiteSpace, we systematically examined information regarding countries, institutions, authors, journals, and keywords.

resultsA total of 573 literature on HER2-low expression breast cancer was included. These literature come from 54 countries, 1145 institutions, and 4125 authors. China and the United States emerge as leading contributors to this field, with the Harvard University being the most prolific institution.Curigliano is the most influential scholar in this research domain.The leading journals in terms of literature sources are CANCERS and FRONTIERS IN ONCOLOGY.The most cited reference is "Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer".Keyword analysis indicates that the research emphasis has shifted towards "prognostic factor", "immunohistochemistry", "targeted therapy", "diagnosis", "guideline", "overall survival" and "pathological complete response" in recent years.

conclusionThis study applies bibliometric tools to analyze the literature on HER2-low expression breast cancer, which shows a notable upward trend and highlights the clinical significance, providing researchers with the priorities and hotspots in this crucial field.

Indexed as

BibliometricsBreast cancerClinical prognosisHER2-low expressionMolecular pathological characteristicsResearch status

Identifiers

PMID41258561
PMCPMC12748448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.