ArticleEuropean geriatric medicine2026
Potentially inappropriate prescriptions in acutely admitted older patients: a development study to create a clinical decision support tool using a Delphi process.
Article in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeOlder patients admitted with acute illness face a high risk of adverse drug events (ADEs), yet no clinical decision support (CDS) tool currently exists to guide pharmacotherapy in this population during the early phase of hospitalization. This development study aimed to establish expert consensus on drugs that should be used with caution or avoided in acutely admitted older patients in specific clinical situations.
methodsA three-round Delphi study was conducted among 26 experienced physicians in Clinical Pharmacology, Emergency Medicine, and Geriatric Medicine. Panel members rated statements on potentially inappropriate prescriptions (PIPs) across nine clinical situations (e.g., hypotension, hypoglycemia, dehydration). Statements were rated on a five-point Likert scale; consensus was defined as ≥ 75% agreement for or ≥ 50% agreement against. Questionnaires were administered via REDCap.
resultsConsensus was reached on 127 of 138 statements (81 accepted and 46 rejected, total 92%) across three Delphi rounds. An additional 8 statements were accepted following author review, resulting in a final list of 89 PIP-situation combinations. Drugs, such as ACE inhibitors, insulin, diuretics, and sedatives, were frequently identified as problematic across multiple situations. Common concerns among the experts included abrupt withdrawal of potentially inappropriate medications in situations, where this could be detrimental to the patient, and it was underscored, that other courses of action would often be better (e.g., increasing observations or reducing dose).
conclusionWe developed a CDS tool to identify PIPs in acutely admitted older adults. Based on expert consensus, it addresses a key gap in acute geriatric care. Future studies will aim to validate the tool.
Indexed as
Identifiers
41258578What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.