Overdose-Related Cardiac Arrest in the Era of the Opioid Epidemic.

Ryan Jj Buckley, David Yang, Gail D'Onofrio, Sarah M Perman

Abstract readReview

In one paragraph

Review in Critical care clinics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Higher prevalence of non-fatal overdose with opioid and stimulant use compared to use of opioids alone.Drug and alcohol dependence · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan Jj BuckleySection of Pulmonary, Critical Care & Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA; Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA. Electronic address: Ryan.Buckley@yale.edu.

David YangDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.

Gail D'OnofrioDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.

Sarah M PermanDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.

Funding

Yale Drug use, Addiction and HIV Research Scholars (DAHRS)K12DA033312 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Patrick O'Connor · 2013 to 2026

$7.2M

NIDA NIH HHS K12 DA033312

6 · The paper itself

Abstract

This article reviews the multifaceted landscape of overdose-associated out-of-hospital cardiac arrest in the context of the ongoing opioid epidemic and opioid-associated. It synthesizes current knowledge on epidemiology, pathophysiology, prehospital and hospital management, outcomes, and prevention strategies. The article emphasizes the clinical nuances of polysubstance overdoses, postarrest care, and highlights critical gaps in research, especially around naloxone use and postresuscitation care.

Indexed as

Analgesics, OpioidDrug OverdoseOpiate OverdoseOpioid EpidemicOut-of-Hospital Cardiac ArrestHumansNaloxoneNarcotic AntagonistsAnalgesics, OpioidNaloxoneNarcotic AntagonistsFentanyl toxicityNaloxone interventionOpioid-associated cardiac arrestOut-of-hospital cardiac arrestOverdose-related cardiac arrestPolysubstance overdose

Identifiers

PMID41260714

DOI10.1016/j.ccc.2025.08.008

PMCPMC13286586

What Socratic holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.