Evidence map›Paper›PMID 41262069›Full record

ReviewFEBS letters2026

The role and implications of mammalian cellular circadian entrainment.

Priya Crosby

Abstract readReview
In one paragraph

Review in FEBS letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Priya CrosbyInstitute of Cell Biology, School of Biological Sciences, University of Edinburgh, UK.ORCID 0000-0002-7532-7708

Funding

Royal Society RG\R1\251371Wellcome Trust 320953/Z/24/Z
6 · The paper itself

Abstract

The ability to align circadian phase to specific cues, or 'entrainment', is a defining feature of a circadian rhythm. Entrainment is critical for useful circadian function, as it enables organisms to determine the specific time of day to perform temporally restricted behavioural and physiological activities, ranging from sleep to cell division. While mammals have long been known to entrain their circadian rhythm, recent work has shed light on how this is achieved in every single cell, all of which maintain their own individual circadian oscillation. Here I will highlight the current understanding of how the major entraining cues of light, feeding and temperature are communicated to cells to alter their phase. Knowledge of the mechanisms of cellular entrainment has the capacity to impact both fundamental understanding of circadian rhythms and our application of cellular circadian research to real-world problems, including shift work.

Indexed as

Circadian RhythmMammalsAnimalsCircadian ClocksHumansLightTemperaturecell biologycell signallingcircadianentrainmentPERIOD

Identifiers

PMID41262069
PMCPMC13022746

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.