Evidence map›Paper›PMID 41263449›Full record

ReviewInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Prevention of stillbirths associated with umbilical cord abnormalities: A clinico-pathological overview.

Laura Avagliano, Chiara Parodi, Valentina Massa, Gaetano Bulfamante

Abstract readReview
In one paragraph

Review in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura AvaglianoUniversity of Milan, Milan, Italy.ORCID https://orcid.org/0000-0002-7808-7578
Chiara ParodiDepartment of Health Sciences, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0002-2689-2049
Valentina MassaDepartment of Health Sciences, University of Milan, Milan, Italy.
Gaetano BulfamanteDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stillbirths affect millions of pregnancies every year worldwide, and obstruction of the umbilical cord blood flow is one of the main causes of fetal death. This review provides a clinico-pathological overview of cord abnormalities potentially associated with antepartum stillbirth, describing the mechanism determining the death and addressing suggestions about the possibility of stillbirth prevention. Fatal effects on the fetal circulatory system can occur due to various umbilical cord abnormalities, both in cases of acquired anomalies (i.e., multiple tight nuchal cords and true knots) or congenital anomalies (i.e., aneurysmatic malformation, stricture, abnormalities of cord insertion in the fetal or placenta site such as velamentous or furcate cord insertion). In pregnancies with an identification of umbilical cord abnormality, ultrasound signs of fetal well-being could be monitored over time. Although close monitoring cannot prevent a sudden lethal obstruction of umbilical cord vessels, it could identify the development of long-lasting signs of fetal decompensation, possibly preventing fetal death.

Indexed as

Fetal DeathStillbirthUmbilical CordFemaleHumansNuchal CordPregnancyUltrasonography, Prenatalknotnuchal cordplacentapregnancystillbirthstrictureultrasoundumbilical cordvelamentous insertion

Identifiers

PMID41263449
PMCPMC13094681

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.