Evidence map›Paper›PMID 41263952›Full record

ArticleEuropean child & adolescent psychiatry2026

The impact of critical periods of maternal generalized anxiety disorder on mental health problems in preschoolers: a Brazilian study of young mothers.

Daniele Behling de Mello, Carolina Coelho Scholl, Jéssica Puchalski Trettim, Fernanda Teixeira Coelho, Jaqueline Buzetto Silveira, Andressa Jacondino Pires, Bárbara Borges Rubin, Luciana de Avila Quevedo, Karen Amaral Tavares Pinheiro, Ricardo Tavares Pinheiro and 1 more

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Article in European child & adolescent psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniele Behling de MelloPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil.
Carolina Coelho SchollPostgraduate Program in Epidemiology, Federal University of Pelotas (UFPel) Marechal Deodoro, 1160, Pelotas, RS, 96020-220, Brazil.
Jéssica Puchalski TrettimPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil.
Fernanda Teixeira CoelhoPostgraduate Program in Biological Sciences: Biochemistry, Federal University of Rio Grande do Sul (UFRGS) Ramiro Barcelos, 2600-Santa Cecília, Porto Alegre, RS , 90035-003, Brazil.
Jaqueline Buzetto SilveiraPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil.
Andressa Jacondino PiresPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil.
Bárbara Borges RubinPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil.
Luciana de Avila QuevedoPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil.
Karen Amaral Tavares PinheiroFaculty of Medicine, Federal University of Rio Grande (FURG), Av. Itália - Km 8 - Carreiros, Rio Grande, RS, 96203-900, Brazil.
Ricardo Tavares PinheiroPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil.
Mariana Bonati de MatosPostgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel) Gonçalves Chaves, 373/411, RS, 96015-560, Pelotas, Brazil. marianabonatidematos@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the impact of critical periods of maternal Generalized Anxiety Disorder (GAD) on mental health problems in preschoolers from a city in Southern Brazil. This cohort study included 328 pregnant adolescents and their children who were assessed in three stages (prepartum, postpartum, and at 4-5 years of age). The Mini International Neuropsychiatric Interview Plus (MINI PLUS) was used to assess maternal mental health, and the Strengths and Difficulties Questionnaire (SDQ) was used to assess child mental health. children of mothers with GAD only during pregnancy showed a higher risk of peer relationship problems (IRR: 3.57; p = 0.040) compared to children of mothers with no history of GAD. In turn, children of mothers with GAD only when the child was 4-5 years old had a higher risk of conduct problems (IRR: 2.77; p = 0.001), hyperactivity (IRR: 1.99; p < 0.028), and total problems (IRR: 3.26; p = 0.001) compared to children of mothers with no history of GAD. Maternal GAD at different periods was associated with different child mental health problems, highlighting the need for targeted preventive interventions.

Indexed as

Anxiety DisordersChild of Impaired ParentsGeneralized Anxiety DisorderMothersPregnancy ComplicationsPrenatal Exposure Delayed EffectsAdolescentAdultBrazilChild, PreschoolCohort StudiesFemaleHumansMalePregnancyAnxiety disordersBehavior problemsChild behaviorMaternal and child healthPregnancy in adolescencePreschoolers

Identifiers

PMID41263952

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.