Evidence mapPaperPMID 41266104Full record

ArticleBMJ paediatrics open2025

Comparison of nSOFA and RSS for predicting bronchopulmonary dysplasia in preterm infants: a retrospective cohort study.

Doudou Xu, Ziyi Tian, Mali Xu, Peipei Hu, Shupeng Wang, Yang Wang, Shenggang Ding

Abstract readComparative Study
In one paragraph

Article in BMJ paediatrics open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Doudou Xu *Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.ORCID http://orcid.org/0000-0002-2413-2601
Ziyi Tian *Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Mali XuDepartment of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Peipei HuDepartment of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Shupeng WangDepartment of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yang WangDepartment of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China w.yang126@126.com dingsg@ahmu.edu.cn.ORCID http://orcid.org/0000-0003-3376-267X
Shenggang DingDepartment of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China w.yang126@126.com dingsg@ahmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to compare the efficacy of the Neonatal Sequential Organ Failure Assessment (nSOFA) and the Respiratory Severity Score (RSS) in predicting Bronchopulmonary Dysplasia (BPD).

methodsWe conducted a retrospective study that included preterm infants who required invasive mechanical ventilation (IMV) within 24 hours of birth. The accuracy of each scoring system was assessed and compared using the area under the curve (AUC) derived from receiver operating characteristic (ROC) analysis. Additionally, Spearman's correlation was used to evaluate the association between RSS and nSOFA, and logistic regression models were constructed to adjust for potential confounders.

resultsA total of 85 preterm infants were analysed, of whom 53 (62.4%) were diagnosed with BPD. Both nSOFA and RSS demonstrated strong predictive abilities for BPD, with AUCs of 0.82 and 0.81, respectively. Logistic regression analysis indicated that the relationship between the two scoring systems and BPD remained stable. However, nSOFA exhibited better predictive accuracy than RSS (0.75 vs 0.69). A significant positive correlation was observed between nSOFA and RSS (r=0.707, p<0.001).

conclusionsIn preterm infants requiring IMV, both nSOFA and RSS are effective predictors of BPD, with nSOFA showing superior accuracy.

Indexed as

Bronchopulmonary DysplasiaOrgan Dysfunction ScoresFemaleHumansInfant, NewbornInfant, PrematureLogistic ModelsMalePredictive Value of TestsRespiration, ArtificialRetrospective StudiesROC CurveSeverity of Illness IndexIntensive Care Units, NeonatalNeonatology

Identifiers

PMID41266104
PMCPMC12625845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.