Evidence map›Paper›PMID 41266786›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

The impact of collider bias on genetic prediction in psychotic disorders.

Amna Asim, Yuan Yang, PsyCourse Study, Urs Heilbronner, Thomas Schulze, Todd Lencz, Evangelos Vassos, Sean A P Clouston, Roman Kotov, Katherine Jonas

Abstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amna AsimDepartment of Psychology, Stony Brook University, Stony Brook, NY, USA.
Yuan YangDepartment of Department of Family Population & Preventive Medicine, Stony Brook Medicine, Stony Brook, NY, USA.
PsyCourse Study
Urs HeilbronnerInstitute of Psychiatric Phenomics and Genomic (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0001-7135-762X
Thomas SchulzeInstitute of Psychiatric Phenomics and Genomic (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0001-6624-2975
Todd LenczInstitute of Behavioral Sciences, Feinstein Institutes for Medical Research, Manhasset, NY, USA.ORCID 0000-0001-8586-338X
Evangelos VassosSocial Genetic & Developmental Psychiatry Centre, King's College London, London, UK.ORCID 0000-0001-6363-0438
Sean A P CloustonDepartment of Department of Family Population & Preventive Medicine, Stony Brook Medicine, Stony Brook, NY, USA.ORCID 0000-0002-6124-0329
Roman KotovDepartment of Psychiatry & Behavioral Health, Stony Brook Medicine, Stony Brook, NY, USA.
Katherine JonasDepartment of Psychiatry & Behavioral Health, Stony Brook Medicine, Stony Brook, NY, USA. katherine.jonas@stonybrookmedicine.edu.ORCID 0000-0002-1910-223X

Funding

Trajectories and Determinants of Cognitive Decline in Psychotic Disorders Over 35 YearsR01MH135119 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI Katherine G Jonas, Roman I Kotov · 2024 to 2026
$2.3M
Optimized Phenotypes for Genetic Association StudiesR21MH123908 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI JONAS, KATHERINE G · 2020 to 2020
$448k
NIMH NIH HHS R01 MH135119U.S. Department of Health & Human Services | National Institutes of Health (NIH) R21MH123908U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) MH094398U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) MH110434U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) MH44801
6 · The paper itself

Abstract

Polygenic risk scores (PRS) have potential utility as biomarkers of psychiatric disorders. However, the potential utility of some PRS has been much clearer than others. The schizophrenia PRS has been consistently associated with diagnosis, symptom severity, and other correlates of schizophrenia. Yet despite the close genetic correlation (r

Indexed as

Bipolar DisorderGenetic Predisposition to DiseaseMultifactorial InheritancePsychotic DisordersSchizophreniaAdultCase-Control StudiesCohort StudiesFemaleHumansMaleMiddle Aged

Identifiers

PMID41266786
PMCPMC12708778

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.