Evidence map›Paper›PMID 41268343›Full record

ReviewBioactive materials2025

Preclinical research models for evaluating the biocompatibility of bioresorbable metallic cardiovascular stents: A comparative review.

Samuel Hansen, Thuy Anh Bui, Xiaoxue Xu, Kristine McGrath

Abstract readReview
In one paragraph

Review in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel HansenSchool of Life Sciences, Faculty of Science, University of Technology Sydney, 745 Harris St, Ultimo, NSW, Australia, 2007.
Thuy Anh BuiSchool of Biomedical Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, 81-113 Broadway, Ultimo, NSW, Australia, 2007.
Xiaoxue XuSchool of Biomedical Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, 81-113 Broadway, Ultimo, NSW, Australia, 2007.
Kristine McGrathSchool of Life Sciences, Faculty of Science, University of Technology Sydney, 745 Harris St, Ultimo, NSW, Australia, 2007.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular stents are widely used to treat atherosclerosis by relieving vascular obstruction and providing structural support after coronary angioplasty. Bioresorbable metallic stents represent a promising alternative to conventional corrosion-resistant stents, which are linked to late-stage complications such as in-stent restenosis and thrombosis. Due to the diversity of stent materials and designs, rigorous evaluation of their interactions with the vascular environment in relevant preclinical models is essential before clinical translation. However, current studies employ highly variable in vitro cell systems, in vivo animal models, and experimental assays to assess biocompatibility, making it difficult to draw definitive conclusions about candidate designs. This review outlines the current landscape of bioresorbable metallic stents, critically examines the strengths and limitations of preclinical models described in the literature and in international guidelines, and provides recommendations to guide future research in this rapidly evolving field.

Indexed as

AtherosclerosisBiodegradable metalsBioresorbable stentsPreclinical models

Identifiers

PMID41268343
PMCPMC12628057

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.