Evidence mapPaperPMID 41268524Full record

ArticleFrontiers in cardiovascular medicine2025

Investigation of the effect of quercetin on experimental traumatic cardiac injury in rats.

Muhammed Enes Taysi, Mustafa Enes Demirel, Ayhan Cetinkaya, Aslihan Saylan, Seyit Ali Kayis, Murat Alisik

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muhammed Enes TaysiDivision of Emergency Medicine, Cankiri State Hospital, Cankiri, Türkiye.
Mustafa Enes DemirelDepartment of Emergency Medicine, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Türkiye.
Ayhan CetinkayaDepartment of Physiology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Türkiye.
Aslihan SaylanDepartment of Histology and Embryology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Türkiye.
Seyit Ali KayisDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Türkiye.
Murat AlisikDepartment of Medical Biochemistry, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardioprotection is an important aspect of preventive medicine. Quercetin, a plant-derived flavonoid with antioxidant and anti-inflammatory properties, has been linked to reduced cardiovascular risk. Objective: To investigate the cardioprotective effects of quercetin in rats with traumatic cardiac injury (TCI). Methods: Fifty-two Wistar Albino rats were randomly divided into six groups: control ( Results: GPx elevation was detected only at 10 and 20 mg/kg (vs. TCI; Conclusions: Quercetin, especially at 40 mg/kg, may help prevent secondary cardiac injury after trauma by reducing oxidative stress and limiting histopathological damage. These results support quercetin's cardioprotective potential and warrant confirmation in larger preclinical models with broader designs.

Indexed as

antioxidantblunt cardiac injuryinterleukin-33malondialdehydequercetinrat model

Identifiers

PMID41268524
PMCPMC12626915

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.