Evidence map›Paper›PMID 41268634›Full record

ArticleAnnals of medicine2025

The clinical characteristics and prognosis in chronic obstructive pulmonary disease patients with anorexia.

Qing Song, Dan Peng, Ping Zhang, Tao Li, Cong Liu, Ling Lin, Yuqin Zeng, Ping Chen

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Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Qing SongDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Dan PengThe Fourth People's Hospital of Nanchang County, Nanchang, Jiangxi, China.
Ping ZhangDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Tao LiDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Cong LiuDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ling LinDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0003-4816-1834
Yuqin ZengDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ping ChenDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0001-6707-8636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnorexia is a common problem among patients with chronic obstructive pulmonary disease (COPD). This study aimed to analyze the clinical characteristics and prognosis of COPD patients with anorexia.

methodsThis prospective cohort study included patients registered in the RealDTC study between May 2023 and February 2024. Demographic on COPD Assessment Test (CAT) and modified Medical Research Council (mMRC) scores, pulmonary function, number of exacerbations, inhalation therapy, and the section of anorexia/cachexia subscale (A/CS)-12 of Functional Assessment of Anorexia/Cachexia Therapy (FAACT) scores were collected. A FAACT A/CS-12 score of ≤ 30 was used to identify patients with anorexia. All patients were followed up for one year to collect exacerbations, and mortality.

resultsA total of 758 patients with COPD were enrolled, 132 (17.4%) of whom had anorexia. Patients with anorexia had higher age, CAT and mMRC scores, number of exacerbations, and worse pulmonary function. Logistic regression analysis showed that CAT scores of 10-19 (OR = 2.867, 95% CI = 1.423-5.773), 20-29 (OR = 6.932, 95% CI = 3.234-14.857) and ≥ 30 (OR = 67.355, 95% CI = 7.221-628.271), and number of hospitalizations ≥ 1 (OR = 2.041, 95% CI = 1.347-3.093) were independent risk factors for anorexia (

conclusionsThe COPD patients with anorexia had worse pulmonary function, higher symptoms burden, and risk of exacerbation and hospitalization.

Indexed as

AnorexiaPulmonary Disease, Chronic ObstructiveAgedDisease ProgressionFemaleHumansMaleMiddle AgedPrognosisProspective StudiesRespiratory Function TestsSeverity of Illness IndexanorexiaChronic obstructive pulmonary diseaseexacerbationpulmonary functionsymptom scores

Identifiers

PMID41268634
PMCPMC12642890

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.