Evidence map›Paper›PMID 41269005›Full record

ArticleJournal of proteome research2025

Comparative Proteomic Profiling of Adrenocortical Neoplasia Using Mass Spectrometry.

Jean Lucas Kremer, Henrique Sanchez Ortega, Talita Siqueira-Souza, Claudia Blanes Angeli, Leo Kei Iwai, Claudimara Ferini Pacicco Lotfi

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jean Lucas KremerInstitute of Biomedical Sciences, Department of Anatomy, University of São Paulo, Av. Prof. Lineu Prestes, 2415, Butantan, São Paulo 05508-000, Brazil.ORCID 0000-0002-0053-8500
Henrique Sanchez OrtegaInstitute of Biomedical Sciences, Department of Anatomy, University of São Paulo, Av. Prof. Lineu Prestes, 2415, Butantan, São Paulo 05508-000, Brazil.
Talita Siqueira-SouzaSchool of Medicine, Department of Clinical Medicine, University of São Paulo, Av. Dr. Arnaldo, 455, Cerqueira Cesar, Brazil 01246903 São Paulo.
Claudia Blanes AngeliInstitute of Biomedical Sciences, Department of Parasitology, University of São Paulo, Av. Prof. Lineu Prestes, 1374, Butantan, São Paulo 05508-000, Brazil.
Leo Kei IwaiButantan Institute, Laboratory of Applied Toxicology, Center of Toxins, Immune-response and Cell Signaling LETA/CeTICS Laboratory, Av. Vital Brasil, 1500 - Butantã, São Paulo 05503-900, Brazil.
Claudimara Ferini Pacicco LotfiInstitute of Biomedical Sciences, Department of Anatomy, University of São Paulo, Av. Prof. Lineu Prestes, 2415, Butantan, São Paulo 05508-000, Brazil.ORCID 0000-0002-9881-7099

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in high-throughput molecular analysis have significantly enhanced our understanding of the molecular mechanisms underlying adrenocortical diseases. To identify differences in protein signatures that may reveal insights into disease-specific pathogenesis, we used LC-MS/MS and bioinformatics to compare proteomic profiles of normal human adrenal (NHA) tissue, adrenocortical adenomas (ACA), adrenocortical carcinomas (ACC), and primary macronodular adrenocortical hyperplasia (PMAH) tumors, with and without

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical AdenomaAdrenocortical CarcinomaProteomeProteomicsAdultArmadillo Domain ProteinsChromatography, LiquidFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedMutationTandem Mass SpectrometryTumor Suppressor ProteinsArmadillo Domain ProteinsARMC5 protein, humanProteomeTumor Suppressor Proteinsadrenal glandadrenocortical neoplasiabioinformaticsproteome

Identifiers

PMID41269005
PMCPMC12687312

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.