ReviewJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2026
What goes down may come up: regurgitative behaviors and their underlying gut-brain axes-insights from genetic models and related pathologies.
Review in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Most humans have experienced regurgitation and vomiting (emesis) at some point in their lives. These behaviors are also commonly observed throughout the rest of the animal kingdom, serving various functions such as feeding, courtship, defense against predators, and protection from accidental toxin ingestion. Studying these behaviors offers valuable insights into the underlying gut-brain axis and presents opportunities to identify new therapeutic targets. However, detailed mechanistic studies on the molecular, genetic, and neural circuit basis of regurgitative behaviors have been hampered until recently due to the lack of suitable genetic model organisms capable of regurgitation. This review introduces researchers to the mechanisms of regurgitative behaviors, particularly those related to the gut-brain axis. We summarize these behaviors across different taxa, review current knowledge of their underlying mechanisms with a focus on gut-brain connections, and discuss related pathologies. Finally, we present recent findings from Drosophila models of regurgitation and emesis, and outline key questions that still require attention.
Indexed as
Identifiers
41269312What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.