ArticleActa neurochirurgica2025
Prognostic value of the preoperative study of cerebrospinal fluid dynamics in Chiari malformations: a pilot study.
Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Craniocervical Junction Morphology and Cerebrospinal Fluid Spaces at the Foramen Magnum in Idiopathic Intracranial Hypertension: Implications for Pathophysiology.Journal of clinical medicine · 2026Article
- CSF stroke volume measured in pediatric Chiari type 1 Malformation subjects before and after posterior fossa decompression surgery compared with healthy subjects.Fluids and barriers of the CNS · 2026Article
- Evaluating CSF Flow (Cine MR) and Clinical Outcomes in Patients with Chiari Type 1 Who Underwent Dural Relaxation or Durotomy.Brain sciences · 2026Article
- Editorial: Cerebrospinal fluid flow imaging in Chiari Malformation type 1.Acta neurochirurgica · 2025Article
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5 authors.
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Abstract
purposeIn patient with Chiari type I malformations (CM1), indication for surgery can be difficult to establish. Headaches are a common complaint. Factors that predict headache relief have not been clearly identified. Several studies have aimed to examine cerebrospinal fluid (CSF) hydrodynamics in patients with CM1 by using phase-contrast MRI (pcMRI), which is currently the only non-invasive method for assessing craniospinal hydrodynamics and hemodynamics. People with CM1 present alterations in cerebrospinal fluid (CSF) and cerebral blood dynamics. The objective of the present study was to identify hydrodynamic criteria that are predictive of positive clinical outcome (headache relief) after posterior fossa decompression surgery in patient with CM1.
method41 patients who underwent posterior fossa decompression surgery at Amiens-Picardie University Hospital (Amiens, France) between 2016 and 2021 were retrospectively included. We used preoperative pcMRI to analyze CSF dynamics. Stroke volumes of cerebrospinal fluid were quantified at the aqueduct of Sylvius (SV
results12 patients reported headache relief. The mean SV
conclusionSVaqu may have prognostic value for headache relief following surgery for CM1. Further investigation is warranted. This association is likely related to the recruitment of intraventricular pulsatility, which may help regulate potential intracranial pressure changes. Notably, this pulsatility does not appear to be linked to morphological features.
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