Evidence map›Paper›PMID 41269404›Full record

ReviewDiscover oncology2025

Exploring the biological mechanisms of obesity affecting breast cancer from a multidimensional perspective.

Yingying Rao, Suyuan Wang, Xianglin Liu, Changhua Shao, Hengyu Li

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingying Rao *Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Suyuan Wang *The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Xianglin Liu *Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Changhua ShaoDepartment of Breast and Thyroid Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Hengyu LiDepartment of Breast and Thyroid Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China. lhy@smmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, a global health challenge, significantly contributes to breast cancer pathogenesis through chronic inflammation and metabolic dysregulation. This review summarizes the biological mechanisms through which obesity influences the development and progression of breast cancer, focusing on endocrine regulation, intercellular communication, gut microbiota interactions, obesity-associated genetic polymorphisms, and circadian rhythm homeostasis. The aim is to provide a theoretical foundation for the diagnosis and treatment of obesity-related breast cancer.

Indexed as

Biological mechanismsBMIBreast cancerCircadian homeostasisHigh-fat dietIntestinal microecologyObesityTumor immune microenvironment

Identifiers

PMID41269404
PMCPMC12638480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.