Evidence map›Paper›PMID 41269443›Full record

ReviewSports medicine - open2025

Cross-Education of Strength: From Theory to Practice in Contemporary Sports Rehabilitation-A Narrative Review and Clinical Implications.

Mauro Mirto, Fabio Esposito, F Marcello Iaia, Roberto Codella

Registry-linked trialAbstract readReview
In one paragraph

Review in Sports medicine - open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07510737 (The Effect of Cross Training on Clinical and Functional Outcomes in Frozen Shoulder Rehabilitation), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07510737 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Cross Training on Clinical and Functional Outcomes in Frozen Shoulder Rehabilitation

TypeobservationalSponsorInonu UniversityRan2026 to 2026Enrolled38ConditionsFrozen ShoulderArmsStandard Physical Therapy Group, Cross-Education Group
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mauro MirtoDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.ORCID http://orcid.org/0009-0008-9187-6150
Fabio EspositoDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.ORCID http://orcid.org/0000-0002-4420-2611
F Marcello IaiaDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.ORCID http://orcid.org/0000-0003-0981-6471
Roberto CodellaDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy. roberto.codella@unimi.it.ORCID http://orcid.org/0000-0003-1608-1899

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCross-education (CE) of strength refers to strength gains in the untrained limb after unilateral resistance training. Despite the long-standing recognition of this phenomenon, its potential implications in clinical and rehabilitation settings have only been studied extensively in recent decades. MAIN BODY: The implementation of unilateral resistance training in early-stage sports rehabilitation remains underrated, likely due to the lack of consensus on evidence-based guidelines. Thus, this narrative review provides a current overview of the CE of strength, analyzes its practical implications for sports rehabilitation, and examines the training modalities and parameters that should be modulated to optimize CE adaptations, thereby supporting early intervention against post-injury neuromuscular decline.

conclusionsUnilateral resistance training in the healthy limb appears to represent a cost-effective and accessible rehabilitation strategy for athletes who are unable to work on their injured limb from the early stages of rehabilitation. This strategy may ensure the maintenance of muscle strength levels in the trained limb while minimizing neuromuscular decline in the injured and immobilized limb. CE of strength may be implemented as an addition to traditional early-stage rehabilitation strategies, such as pain, swelling, and inflammation reduction, the progressive restoration of joint range of motion, and the progressive strength training in sports injury rehabilitation. Further research is required to make definitive recommendations.

Indexed as

Cross-educationSports rehabilitationStrength training

Identifiers

PMID41269443
PMCPMC12638512

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.